Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | PTGIR | P43119 | 11/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 7/20 | 0.40 |
| ▸ | CKS1B | P61024 | 4/20 | 0.40 |
| ▸ | SKP1 | P63208 | 4/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 4/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5212415 | 0.92 | PTGIR (0.46) | ACHEPTGIRPTGDRCKS1BSKP1 | |
| SCHEMBL5217715 | 0.86 | CKS1B (0.43) | ACHEPTGIRPTGDRCKS1BSKP1 | |
| SCHEMBL5211053 | 0.80 | CKS1B (0.48) | ACHEPTGIRPTGDRCKS1BSKP1 | |
| SCHEMBL7494420 | 0.74 | PTGIR (0.45) | ACHEPTGIRBCHEMAOAMAOB | |
| SCHEMBL7485192 | 0.74 | PTGIR (0.48) | ACHEPTGIRPTGDR | |
| SCHEMBL7497308 | 0.73 | PTGIR (0.49) | PTGIR | |
| SCHEMBL5214413 | 0.71 | CKS1B (0.48) | PTGIRPTGDRCKS1BSKP1SKP2 | |
| SCHEMBL5214583 | 0.71 | PTGIR (0.57) | PTGIRPTGDR | |
| SCHEMBL5214397 | 0.70 | NR1I2 (0.63) | PTGIRPTGDRCKS1BSKP1SKP2 | |
| SCHEMBL7492835 | 0.70 | PTGIR (0.44) | ACHEPTGIRTBXA2RHTR2AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7205302-B2 | Anticoagulants; antilipemic agents; cardiovascular disorders | NIPPON SHINYAKU CO., LTD. (JP) | 2007-04-17 | — | — | US | disclosed |
| EP-1400518-B1 | HETEROCYCLIC COMPOUND DERIVATIVES AND MEDICINES | NIPPON SHINYAKU CO LTD (JP) | 2007-01-17 | — | — | EP | disclosed |
| US-20040102436-A1 | Heterocyclic compound derivatives and medicines | NIPPON SHINYAKU CO., LTD. (JP) | 2004-05-27 | — | — | US | disclosed |
| EP-1400518-A1 | HETEROCYCLIC COMPOUND DERIVATIVES AND MEDICINES | Nippon Shinyaku Co., Ltd. (JP) | 2004-03-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102436-A1 | Heterocyclic compound derivatives and medicines | CNR2, CNR1, GPR55 | ACHE 3467/4885PTGIR 30/4885PTGDR 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.