Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | APEX1 | P27695 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 10/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL331665 | 0.92 | POLB (0.58) | POLBAPEX1HTTTDP1L3MBTL1 | |
| SCHEMBL24103806 | 0.92 | POLB (0.64) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL28725903 | 0.89 | POLB (0.63) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL17036971 | 0.89 | POLB (0.63) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL28035136 | 0.88 | POLB (0.55) | POLBAPEX1HTTTDP1L3MBTL1 | |
| SCHEMBL14173281 | 0.87 | HTT (0.68) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL14173280 | 0.87 | HTT (0.68) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL7003272 | 0.87 | POLB (0.60) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL11372567 | 0.86 | POLB (0.67) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL690787 | 0.86 | HTT (0.67) | POLBAPEX1HTTTDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1388540-B1 | ACRYLIC ESTERS AND USE THEREOF | MITSUI CHEMICALS INC (JP) | 2007-09-05 | — | — | EP | disclosed |
| EP-1302471-B1 | SULFUR COMPOUND AND USE THEREOF | MITSUI CHEMICALS INC (JP) | 2006-12-27 | — | — | EP | disclosed |
| US-6835844-B2 | Acrylic esters and use thereof | MITSUI CHEMICALS, INC. (JP) | 2004-12-28 | — | — | US | disclosed |
| US-20040102592-A1 | Acrylic esters and use thereof | MITSUI CHEMICALS, INC. (JP) | 2004-05-27 | — | — | US | disclosed |
| EP-1388540-A1 | ACRYLIC ESTERS AND USE THEREOF | Mitsui Chemicals, Inc. (JP) | 2004-02-11 | — | — | EP | disclosed |
| US-6570025-B1 | Photopolymerization | MITSUI CHEMICALS, INC. (JP) | 2003-05-27 | — | — | US | disclosed |
| EP-1302471-A1 | SULFUR COMPOUND AND USE THEREOF | Mitsui Chemicals, Inc. (JP) | 2003-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102592-A1 | Acrylic esters and use thereof | RPS4Y1, EPB41, RPS4X | POLB 4436/4885APEX1 1995/4885HTT 4063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.