Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | APEX1 | P27695 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28626767 | 0.96 | POLB (0.56) | POLBAPEX1HTTTDP1ALDH1A1 | |
| SCHEMBL28355151 | 0.96 | HTT (0.67) | POLBAPEX1HTTTDP1ALDH1A1 | |
| SCHEMBL27483797 | 0.96 | HTT (0.67) | POLBAPEX1HTTTDP1ALDH1A1 | |
| SCHEMBL28818378 | 0.96 | HTT (0.67) | POLBAPEX1HTTTDP1ALDH1A1 | |
| SCHEMBL2154214 | 0.94 | ALDH1A1 (0.58) | POLBAPEX1HTTTDP1ALDH1A1 | |
| SCHEMBL29007046 | 0.94 | POLB (0.61) | POLBAPEX1HTTTDP1ALDH1A1 | |
| SCHEMBL23014454 | 0.93 | POLB (0.53) | POLBAPEX1HTTTDP1ALDH1A1 | |
| SCHEMBL17036971 | 0.91 | POLB (0.63) | POLBAPEX1HTTTDP1ALDH1A1 | |
| SCHEMBL28725903 | 0.91 | POLB (0.63) | POLBAPEX1HTTTDP1ALDH1A1 | |
| SCHEMBL68457 | 0.91 | POLB (0.60) | POLBAPEX1HTTTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019141-B1 | HARDENABLE DENTAL COMPOSITION CONTAINING A MIXTURE OF AGGLOMERATED AND AGGREGATED NANOPARTICLES, KIT OF PARTS AND USE THEREOF | 3M INNOVATIVE PROPERTIES CO (US) | 2022-08-31 | — | — | EP | claimed |
| US-5863989-A | ACRYLATE-CONTAINING ADHESIVES, LOW ODOR, DURABILITY | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1999-01-26 | — | — | US | claimed |
| EP-4329704-B1 | INITIATOR SYSTEM WITH POLYMERIZABLE THIOUREA COMPONENT, DENTAL COMPOSITION AND USE THEREOF | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) | 2025-10-08 | — | — | EP | disclosed |
| EP-4622590-A1 | CURABLE COMPOSITION FOR USE IN A PROCESS OF TREATING A DENTAL SITUATION IN THE MOUTH OF A PATIENT | Solventum Intellectual Properties Company (US) | 2025-10-01 | — | — | EP | disclosed |
| EP-4558086-A1 | CURABLE COMPOSITION FOR PRODUCING TRANSPARENT ORTHODONTIC ATTACHMENTS | Solventum Intellectual Properties Company (US) | 2025-05-28 | — | — | EP | disclosed |
| US-12274765-B2 | Curable composition for producing a dental composite crown and process of production | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) | 2025-04-15 | — | — | US | disclosed |
| EP-4494627-A2 | TWO-COMPONENT SELF-ADHESIVE DENTAL COMPOSITION, STORAGE STABLE INITIATOR SYSTEM, AND USE THEREOF | Solventum Intellectual Properties Company (US) | 2025-01-22 | — | — | EP | disclosed |
| US-12194113-B2 | Microcapsule with a porous or hollow core and ph-sensitive shell and use thereof | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) | 2025-01-14 | — | — | US | disclosed |
| US-12138323-B2 | Initiator system with polymerizable thiourea component, dental composition and use thereof | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) | 2024-11-12 | — | — | US | disclosed |
| EP-3386462-B1 | TWO-COMPONENT SELF-ADHESIVE DENTAL COMPOSITION, STORAGE STABLE INITIATOR SYSTEM, AND USE THEREOF | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) | 2024-10-23 | — | — | EP | disclosed |
| CN-118338879-A | Curable composition for dental use | 可乐丽则武齿科株式会社 | 2024-07-12 | — | — | CN | disclosed |
| WO-2001076536-A1 | TWO-COMPONENT DENTAL MATERIALS HAVING A LOW SETTING TEMPERATURE | 3M ESPE AG (DE) | 2001-10-18 | — | — | WO | disclosed |
| WO-2001040370-A2 | IONICALLY CROSSLINKED HYDROGELS WITH ADJUSTABLE GELATION TIME | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2001-06-07 | — | — | WO | disclosed |
| US-5883153-A | SUSTAINED RELEASE GLASS IONOMERS | SHOFU INC. (JP) | 1999-03-16 | — | — | US | disclosed |
| EP-0385457-B1 | High surface hardness transparent resin and polymerizable monomer | MITSUI TOATSU CHEMICALS (JP) | 1994-06-01 | — | — | EP | disclosed |
| US-5250723-A | Copolymerizable monomer containing carbamate or thiocarbamate, ether and isopropenylphenyl groups; protective coatings; optical lenses; hardness; scratch, heat and chemical resistances | MITSUI TOATSU CHEMICALS, INC. (JP) | 1993-10-05 | — | — | US | disclosed |
| EP-0385457-A2 | High surface hardness transparent resin and polymerizable monomer | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-09-05 | — | — | EP | disclosed |
| US-4657835-A | LOW ELECTRICAL RESISTANCE | CANON KABUSHIKI KAISHA (JP) | 1987-04-14 | — | — | US | disclosed |
| US-4259075-A | Method of filling a tooth cavity | KURARAY CO., LTD. (JP) | 1981-03-31 | — | — | US | disclosed |
| US-4134930-A | SLURRYING A METHACRYLATE RESIN WITH A BIS/(METHACRYLOXYPOLYETHOXY) PHENYL/PROPANE | G-C DENTAL INDUSTRIAL CORP. (JP) | 1979-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12274765-B2 | Curable composition for producing a dental composite crown and process of production | SEM1, CAD, SMCHD1 | POLB 795/4885APEX1 1585/4885HTT 2001/4885 |
| US-12194113-B2 | Microcapsule with a porous or hollow core and ph-sensitive shell and use thereof | HAMP, FECH, HAO2 | POLB 3589/4885APEX1 511/4885HTT 1477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.