Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 17/20 | 0.74 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5784101 | 0.95 | GPR119 (0.67) | GPR119EGLN2ALDH1A1LMNAMAPT | |
| SCHEMBL3486554 | 0.91 | GPR119 (0.73) | GPR119 | |
| SCHEMBL31753740 | 0.88 | GPR119 (0.59) | GPR119 | |
| SCHEMBL2471189 | 0.86 | MAPT (0.62) | GPR119EGLN2ALDH1A1LMNAMAPT | |
| SCHEMBL7435316 | 0.85 | GPR119 (0.57) | GPR119EGLN2ALDH1A1LMNAMAPT | |
| SCHEMBL2573355 | 0.85 | GPR119 (1.00) | GPR119 | |
| SCHEMBL2573353 | 0.85 | GPR119 (1.00) | GPR119 | |
| SCHEMBL19297554 | 0.84 | GPR119 (0.64) | GPR119ALDH1A1LMNAMAPT | |
| SCHEMBL20046770 | 0.84 | GPR119 (0.57) | GPR119 | |
| SCHEMBL13883908 | 0.84 | GPR119 (0.64) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025262297-A1 | PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 | DARK BLUE THERAPEUTICS LTD (GB) | 2025-12-26 | — | — | WO | disclosed |
| EP-1646620-B1 | SUBSTITUTED PIPERIDINES AS HISTAMINE H3 RECEPTOR LIGANDS | GLAXO GROUP LTD (GB) | 2007-08-15 | — | — | EP | disclosed |
| US-20060247227-A1 | Substituted piperidines as histamine h3 receptor ligands | BAILEY JAMES M | 2006-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247227-A1 | Substituted piperidines as histamine h3 receptor ligands | HRH3, HRH4, HRH1 | GPR119 216/4885EGLN2 733/4885ALDH1A1 2611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.