Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.57 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.52 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2471189 | 0.88 | MAPT (0.62) | GPR119EGLN2ALDH1A1LMNAMAPT | |
| SCHEMBL3486554 | 0.87 | GPR119 (0.73) | GPR119 | |
| SCHEMBL5211568 | 0.85 | GPR119 (0.74) | GPR119EGLN2ALDH1A1LMNAMAPT | |
| SCHEMBL21876731 | 0.85 | GPR119 (0.59) | GPR119ALDH1A1LMNAMAPT | |
| SCHEMBL8352974 | 0.85 | GPR119 (0.59) | GPR119ALDH1A1LMNAMAPT | |
| SCHEMBL24990167 | 0.84 | EGLN2 (0.63) | GPR119EGLN2ALDH1A1LMNAMAPT | |
| SCHEMBL2959519 | 0.84 | GPR119 (0.74) | GPR119ALDH1A1MAPT | |
| SCHEMBL8354642 | 0.84 | GPR119 (0.62) | GPR119ALDH1A1LMNAMAPT | |
| SCHEMBL7344717 | 0.84 | ITGB3 (0.47) | GPR119IRAK4AR | |
| SCHEMBL5235667 | 0.83 | ALDH1A1 (0.57) | GPR119EGLN2ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623120-A1 | PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993014077-A1 | PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |