Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6856182 | 0.91 | THRB (0.40) | THRB | |
| SCHEMBL5208212 | 0.89 | THRB (0.34) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL5208864 | 0.89 | THRB (0.33) | THRB | |
| SCHEMBL6860926 | 0.87 | THRB (0.36) | THRBALDH1A1TP53CYP3A4HSD17B10 | |
| SCHEMBL5209268 | 0.84 | THRB (0.38) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL6861759 | 0.84 | MGLL (0.39) | THRB | |
| SCHEMBL6862965 | 0.84 | GSK3B (0.32) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL6863500 | 0.84 | MAPT (0.33) | THRB | |
| SCHEMBL6860887 | 0.84 | MAPT (0.36) | THRB | |
| SCHEMBL5210291 | 0.82 | THRB (0.38) | THRBALDH1A1TP53CYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1388540-B1 | ACRYLIC ESTERS AND USE THEREOF | MITSUI CHEMICALS INC (JP) | 2007-09-05 | — | — | EP | disclosed |
| EP-1388540-A1 | ACRYLIC ESTERS AND USE THEREOF | Mitsui Chemicals, Inc. (JP) | 2004-02-11 | — | — | EP | disclosed |