Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.48 |
| ▸ | CHIA | Q9BZP6 | 8/20 | 0.44 |
| ▸ | CHIT1 | Q13231 | 7/20 | 0.44 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16360093 | 0.85 | HRH3 (0.53) | HRH3HRH4SIGMAR1CHIACHIT1 | |
| SCHEMBL3075455 | 0.84 | CHIA (0.43) | SIGMAR1CHIACHIT1GRIN2BGFER | |
| SCHEMBL3085764 | 0.83 | HRH3 (0.74) | HRH3HRH4SIGMAR1SLC18A3 | |
| SCHEMBL2839407 | 0.83 | SLC18A3 (0.62) | HRH3HRH4SIGMAR1CHIASLC18A3 | |
| SCHEMBL27820511 | 0.81 | SLC18A3 (0.64) | SIGMAR1CHIASLC18A3GRIN2BOPRM1 | |
| SCHEMBL9451529 | 0.80 | CHIA (0.54) | SIGMAR1CHIACHIT1GFER | |
| SCHEMBL31455232 | 0.79 | TAS2R14 (0.41) | SIGMAR1CHIACHIT1SLC18A3GRIN2B | |
| SCHEMBL6224694 | 0.78 | HRH3 (0.68) | HRH3HRH4SIGMAR1GFER | |
| SCHEMBL12156434 | 0.76 | NFE2L2 (0.56) | — | |
| SCHEMBL14484048 | 0.76 | NFE2L2 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1040103-B1 | ANILIDE DERIVATIVE, PRODUCTION AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2007-03-14 | — | — | EP | disclosed |
| US-6413947-B1 | Anilide derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-07-02 | — | — | US | disclosed |
| US-6268354-B1 | Pharmaceutical composition for antagonizing CCR5 comprising anilide derivative | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-07-31 | — | — | US | disclosed |
| US-6172061-B1 | AIDS THERAPY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-09 | — | — | US | disclosed |
| US-6166006-A | Anilide derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-12-26 | — | — | US | disclosed |
| EP-1040103-A1 | ANILIDE DERIVATIVE, PRODUCTION AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2000-10-04 | — | — | EP | disclosed |
| WO-1999032468-A1 | ANILIDE DERIVATIVE, PRODUCTION AND USE THEREOF | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-01 | — | — | WO | disclosed |