Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 5/20 | 0.52 |
| ▸ | HTR2A | P28223 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3450414 | 0.92 | HPGD (0.67) | MAPTLMNAKDM4EHPGDHSD17B10 | |
| SCHEMBL3451108 | 0.86 | HRH4 (0.64) | MAPTLMNAKDM4EHPGDHSD17B10 | |
| SCHEMBL3451651 | 0.79 | MAPT (0.61) | MAPTLMNAKDM4EHPGDHSD17B10 | |
| SCHEMBL3452028 | 0.77 | HRH4 (0.74) | MAPTLMNAKDM4EHPGDHSD17B10 | |
| SCHEMBL30085626 | 0.76 | TSHR (0.53) | MAPTKDM4EHPGDHSD17B10TSHR | |
| SCHEMBL28895015 | 0.76 | TSHR (0.53) | MAPTKDM4EHPGDHSD17B10TSHR | |
| SCHEMBL11800148 | 0.76 | MAPT (0.61) | MAPTLMNAKDM4EHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL10630848 | 0.75 | DRD2 (0.57) | MAPTLMNAKDM4EHPGDTSHR | |
| SCHEMBL13309949 | 0.74 | HPGD (1.00) | MAPTLMNAKDM4EHPGDHSD17B10 | |
| SCHEMBL28255854 | 0.73 | MEN1 (0.66) | MAPTLMNAKDM4EHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1796673-A2 | NOVEL PYRIMIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | Reddy US Therapeutics, Inc. (US) | 2007-06-20 | — | — | EP | claimed |
| WO-2006034473-A2 | NOVEL PYRIMIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | REDDY US THERAPEUTICS, INC. (US) | 2006-03-30 | — | — | WO | claimed |