Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | USP7 | Q93009 | 6/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5213542 | 1.00 | HPGD (0.39) | HPGDKDM4EALDH1A1USP7PPARD | |
| SCHEMBL5212662 | 0.86 | ATM (0.41) | ALDH1A1MAPTMEN1KMT2AATM | |
| SCHEMBL5212651 | 0.86 | ATM (0.41) | ALDH1A1MAPTMEN1KMT2AATM | |
| SCHEMBL5672505 | 0.84 | ADORA3 (0.37) | HPGDKDM4EALDH1A1 | |
| SCHEMBL5672508 | 0.84 | ADORA3 (0.37) | HPGDKDM4EALDH1A1 | |
| SCHEMBL5672511 | 0.84 | ADORA3 (0.37) | HPGDKDM4EALDH1A1 | |
| SCHEMBL5217844 | 0.84 | PTGER3 (0.38) | HPGDKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL5673019 | 0.84 | PTGER3 (0.38) | HPGDKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL6185207 | 0.82 | TBXA2R (0.46) | HPGDKDM4EALDH1A1 | |
| SCHEMBL6185200 | 0.82 | TBXA2R (0.46) | HPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1142879-B1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | ASTELLAS PHARMA INC (JP) | 2007-10-10 | — | — | EP | disclosed |
| US-7060721-B1 | Imidazole compounds and medicinal use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2006-06-13 | — | — | US | disclosed |
| EP-1142879-A1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |