Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 12/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5673019 | 1.00 | PTGER3 (0.38) | PTGER3MAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL5215201 | 0.88 | PTGER3 (0.41) | PTGER3LMNATASP1 | |
| SCHEMBL5215186 | 0.88 | PTGER3 (0.41) | PTGER3LMNATASP1 | |
| SCHEMBL5672505 | 0.86 | ADORA3 (0.37) | PTGER3ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL5672508 | 0.86 | ADORA3 (0.37) | PTGER3ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL5672511 | 0.86 | ADORA3 (0.37) | PTGER3ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL5675592 | 0.84 | PTGER3 (0.42) | PTGER3TASP1 | |
| SCHEMBL5675585 | 0.84 | PTGER3 (0.42) | PTGER3TASP1 | |
| SCHEMBL5213542 | 0.84 | HPGD (0.39) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL5213535 | 0.84 | HPGD (0.39) | MAPTALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1142879-A1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | claimed |
| EP-1142879-B1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | ASTELLAS PHARMA INC (JP) | 2007-10-10 | — | — | EP | disclosed |
| US-7060721-B1 | Imidazole compounds and medicinal use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2006-06-13 | — | — | US | disclosed |
| EP-1142879-A1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |