Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5208432 | 0.87 | KDR (0.37) | KDR | |
| SCHEMBL5210824 | 0.87 | KDR (0.40) | KDR | |
| SCHEMBL5210274 | 0.87 | KDR (0.48) | KDR | |
| SCHEMBL5204727 | 0.83 | KDR (0.38) | KDR | |
| SCHEMBL5210148 | 0.82 | ALDH1A1 (0.37) | KDR | |
| SCHEMBL5209198 | 0.82 | DGAT2 (0.34) | KDR | |
| SCHEMBL5210223 | 0.81 | KDR (0.45) | KDR | |
| SCHEMBL5212558 | 0.80 | KDR (0.35) | KDR | |
| SCHEMBL5210055 | 0.80 | KDR (0.41) | KDR | |
| SCHEMBL5207568 | 0.80 | GRM4 (0.33) | KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1585743-B1 | 2-(1H-INDAZOL-6-YLAMINO)- BENZAMIDE COMPOUNDS AS PROTEIN KINASES INHIBITORS USEFUL FOR THE TREATMENT OF OPHTHALMIC DISEASES | PFIZER (US) | 2007-05-23 | — | — | EP | disclosed |