Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11040166 | 0.85 | RAB9A (0.66) | SMN1; SMN2ALDH1A1MAPTRAB9AKMT2A | |
| SCHEMBL5093704 | 0.78 | KMT2A (0.53) | SMN1; SMN2HDAC2HDAC8HDAC6ALDH1A1 | |
| SCHEMBL3266236 | 0.76 | KDM6B (0.62) | SMN1; SMN2ALDH1A1MAPTRAB9AKMT2A | |
| SCHEMBL15295273 | 0.75 | KDM4C (0.78) | — | |
| Hydrochloric Acid SCHEMBL15286677 | 0.74 | KDM4C (0.76) | — | |
| SCHEMBL448129 | 0.73 | KDR (0.59) | SMN1; SMN2ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL13116576 | 0.73 | MAPK1 (0.50) | ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL25303812 | 0.72 | CNR1 (0.66) | SMN1; SMN2RAB9AKMT2ANPC1 | |
| SCHEMBL13986961 | 0.72 | GSK3B (0.55) | SMN1; SMN2HDAC2HDAC8HDAC6ALDH1A1 | |
| SCHEMBL28291764 | 0.71 | TNKS (0.47) | ALDH1A1MAPTRAB9ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362033-B1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | WARNER LAMBERT CO (US) | 2007-04-04 | — | — | EP | claimed |