Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.47 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.43 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.43 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.43 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5840621 | 0.73 | CNR1 (0.54) | CNR1NPC1RAB9APLAAT3PLAAT5 | |
| SCHEMBL25303812 | 0.72 | CNR1 (0.66) | CNR1NPC1RAB9APLAAT3PLAAT5 | |
| SCHEMBL5214482 | 0.71 | SMN1; SMN2 (0.50) | TNKSTNKS2SYKNPC1RAB9A | |
| SCHEMBL250873 | 0.71 | PLAAT3 (0.58) | CNR1NPC1RAB9APLAAT3PLAAT5 | |
| SCHEMBL553085 | 0.70 | KDM4E (0.70) | CNR1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL5840627 | 0.70 | CNR1 (0.54) | CNR1NPC1RAB9APLAAT3PLAAT5 | |
| SCHEMBL4829684 | 0.69 | KDM4E (0.63) | SYKNPC1GAAALDH1A1MAPT | |
| SCHEMBL15401635 | 0.69 | LMNA (0.55) | TNKSTNKS2NPC1RAB9APLAAT3 | |
| SCHEMBL15679867 | 0.69 | NPC1 (0.72) | NPC1RAB9AGAAALDH1A1LMNA | |
| SCHEMBL3872575 | 0.69 | HSP90AA1 (0.58) | NPC1RAB9AGAAHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641878-A | DIPROVOCIM: a new class of effective TLR agonist | 斯克里普斯研究学院 | 2019-04-16 | — | — | CN | disclosed |