Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | NPC1 | O15118 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.61 |
| ▸ | PTAFR | P25105 | 5/20 | 0.60 |
| ▸ | CDK4 | P11802 | 1/20 | 0.60 |
| ▸ | CCND1 | P24385 | 1/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.60 |
| ▸ | NAMPT | P43490 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | CTSV | O60911 | 1/20 | 0.58 |
| ▸ | CTSL | P07711 | 1/20 | 0.58 |
| ▸ | CTSB | P07858 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4662136 | 0.85 | RAB9A (0.83) | RAB9AMEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL2129716 | 0.83 | RAB9A (1.00) | RAB9AMEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL30969954 | 0.83 | RAB9A (1.00) | RAB9AMEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL5218649 | 0.82 | TRPV1 (0.58) | RAB9AMEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL16771883 | 0.81 | P2RX7 (0.52) | RAB9AMEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL2134032 | 0.81 | HDAC1 (0.67) | RAB9AMEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL21045299 | 0.78 | PTAFR (0.62) | RAB9AMEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL29411591 | 0.78 | PTAFR (0.62) | RAB9AMEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL5215127 | 0.78 | EPHX2 (0.50) | RAB9AMEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL1928843 | 0.77 | SMN1; SMN2 (0.65) | RAB9ANPC1KMT2ASMN1; SMN2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581516-A4 | 3-HETEROCYCLIC BENZYLAMIDE DERIVATIVES AS POTASSIUM CHANNEL OPENERS | BRISTOL MYERS SQUIBB CO (US) | 2007-10-17 | — | — | EP | claimed |
| EP-1581516-A2 | 3-HETEROCYCLIC BENZYLAMIDE DERIVATIVES AS POTASSIUM CHANNEL OPENERS | Bristol-Myers Squibb Company (US) | 2005-10-05 | — | — | EP | claimed |
| WO-2004047744-A2 | 3-HETEROCYCLIC BENZYLAMIDE DERIVATIVES AS POTASSIUM CHANNEL OPENERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-06-10 | — | — | WO | claimed |
| EP-4584250-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | Biohaven Therapeutics Ltd. (VG) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024054811-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |