Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4426990 | 0.83 | LMNA (0.56) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL8151932 | 0.82 | LMNA (0.47) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL10511898 | 0.81 | LMNA (0.55) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL8482176 | 0.81 | AOC3 (0.46) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL11600545 | 0.81 | LMNA (0.45) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL8482537 | 0.81 | PPARG (0.41) | KDM4ESMN1; SMN2 | |
| Diphenylmethanol SCHEMBL27859163 | 0.80 | SMN1; SMN2 (0.42) | LMNAKDM4EL3MBTL1AOC3SMN1; SMN2 | |
| SCHEMBL12222364 | 0.79 | LMNA (0.48) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL10615156 | 0.79 | LMNA (0.44) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL8837196 | 0.79 | LMNA (0.44) | LMNAKDM4EL3MBTL1AOC3RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1228367-B1 | AMINOPHENOXYACETAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION CONTAINING THEREOF | ASUBIO PHARMA CO LTD (JP) | 2007-09-26 | — | — | EP | disclosed |
| US-20060178401-A1 | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | DAIICHI ASUBIO PHARMA CO., LTD. | 2006-08-10 | — | — | US | disclosed |
| CN-1264821-C | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | SUNTORY LTD (JP) | 2006-07-19 | — | — | CN | disclosed |
| US-7067533-B2 | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | DAIICHI ASUBIO PHARMA CO., LTD. (JP) | 2006-06-27 | — | — | US | disclosed |
| CN-1449493-A | Aminophenoxyacetamide derivatives and pharmaceutical compositions containing them | SUNTORY LTD (JP) | 2003-10-15 | — | — | CN | disclosed |
| US-20030139447-A1 | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | ASUBIO PHARMA CO., LTD. (JP) | 2003-07-24 | — | — | US | disclosed |
| EP-1228367-A2 | AMINOPHENOXYACETAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION CONTAINING THEREOF | SUNTORY LIMITED (JP) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001079170-A2 | AMINOPHENOXYACETAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION CONTAINING THEREOF | SUNTORY LIMITED (JP) | 2001-10-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139447-A1 | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | SCN10A, CAMK2A, CAMK2B | LMNA 3529/4885KDM4E 1047/4885L3MBTL1 4709/4885 |
| US-20060178401-A1 | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | NR0B1, NR0B2, NR4A1 | LMNA 4085/4885KDM4E 1127/4885L3MBTL1 4531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.