Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | CPT2 | P23786 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5521030 | 0.86 | FFAR1 (0.62) | FFAR1CPT2TDP1KDM4E | |
| SCHEMBL6667493 | 0.82 | FFAR1 (0.52) | FFAR1CPT2TDP1KDM4E | |
| SCHEMBL18760169 | 0.78 | FFAR1 (0.54) | FFAR1CPT2TDP1 | |
| SCHEMBL16280996 | 0.77 | KDM4E (0.42) | FFAR1CPT2TDP1KDM4E | |
| SCHEMBL1578074 | 0.76 | LMNA (0.43) | FFAR1CPT2TDP1KDM4E | |
| SCHEMBL21626032 | 0.76 | FFAR1 (0.39) | FFAR1CPT2TDP1KDM4E | |
| SCHEMBL8965 | 0.75 | SOAT1 (0.37) | FFAR1CPT2TDP1KDM4E | |
| SCHEMBL27312675 | 0.74 | FFAR1 (0.43) | FFAR1CPT2TDP1 | |
| SCHEMBL7083891 | 0.73 | KDM4E (0.36) | FFAR1CPT2TDP1KDM4E | |
| SCHEMBL9065 | 0.73 | KMT2A (0.40) | FFAR1CPT2TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773338-A4 | ACYLATED PIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR AGONISTS | MERCK & CO INC (US) | 2007-08-01 | — | — | EP | disclosed |
| EP-1773338-A2 | ACYLATED PIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR AGONISTS | Merck & Co., Inc. (US) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006020277-A2 | ACYLATED PIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR AGONISTS | MERCK & CO., INC. (US) | 2006-02-23 | — | — | WO | disclosed |