Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.67 |
| ▸ | ACHE | P22303 | 1/20 | 0.67 |
| ▸ | NPY1R | P25929 | 2/20 | 0.65 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.65 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ACP1 | P24666 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | STAT1 | P42224 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14395001 | 0.89 | BCHE (0.67) | BCHEACHENPY1RRIPK1DYRK1A | |
| SCHEMBL5001727 | 0.88 | RIPK1 (0.67) | BCHEACHENPY1RRIPK1DYRK1A | |
| SCHEMBL5219432 | 0.82 | NPC1 (0.52) | BCHEACHENPY1RMAPTNPC1 | |
| SCHEMBL5215844 | 0.81 | RIPK1 (0.61) | BCHEACHENPY1RRIPK1DYRK1A | |
| SCHEMBL17085420 | 0.81 | BCHE (1.00) | BCHEACHENPY1RRIPK1DYRK1A | |
| SCHEMBL5310554 | 0.81 | RIPK1 (0.73) | BCHEACHENPY1RRIPK1DYRK1A | |
| Bromide SCHEMBL17075916 | 0.80 | BCHE (0.98) | BCHEACHENPY1RRIPK1DYRK1A | |
| SCHEMBL14000788 | 0.79 | NPY1R (1.00) | BCHEACHENPY1RRIPK1 | |
| SCHEMBL5213462 | 0.78 | RIPK1 (0.62) | BCHEACHENPY1RRIPK1DYRK1A | |
| SCHEMBL5005571 | 0.78 | RIPK1 (0.72) | BCHEACHENPY1RRIPK1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539724-B1 | AMINO BENZOTHIAZOLE COMPOUNDS WITH NOS INHIBITORY ACTIVITY | NEURAXON INC (CA) | 2007-10-10 | — | — | EP | disclosed |
| EP-1539724-A1 | AMINO BENZOTHIAZOLE COMPOUNDS WITH NOS INHIBITORY ACTIVITY | Neuraxon Inc. (CA) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004014885-A1 | AMINO BENZOTHIAZOLE COMPOUNDS WITH NOS INHIBITORY ACTIVITY | NEURAXON INC. (CA) | 2004-02-19 | — | — | WO | disclosed |