Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 14/20 | 0.58 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5847350 | 1.00 | AVPR1A (0.58) | AVPR1AGPR119MEN1ALDH1A1LMNA | |
| SCHEMBL5216521 | 0.86 | AVPR1A (0.56) | AVPR1AGPR119 | |
| SCHEMBL5215077 | 0.80 | GPR119 (0.57) | GPR119MEN1ALDH1A1LMNATSHR | |
| SCHEMBL5847261 | 0.80 | GPR119 (0.57) | GPR119MEN1ALDH1A1LMNATSHR | |
| SCHEMBL5216708 | 0.79 | AVPR1A (0.64) | AVPR1AGPR119AVPR2KCNH2 | |
| SCHEMBL5216694 | 0.78 | AVPR1A (0.79) | AVPR1AGPR119AVPR2KCNH2 | |
| SCHEMBL15244653 | 0.78 | TP53 (0.50) | MEN1ALDH1A1LMNATSHRKMT2A | |
| SCHEMBL5214016 | 0.77 | AVPR1A (0.61) | AVPR1AGPR119AVPR2KCNH2 | |
| SCHEMBL5215290 | 0.75 | AVPR1A (0.68) | AVPR1AGPR119AVPR2KCNH2 | |
| SCHEMBL3847369 | 0.75 | CCR1 (0.53) | MEN1ALDH1A1LMNATSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558598-B1 | TRIAZOLE COMPOUNDS FOR THE TREATMENT OF DYSMENORRHOEA | PFIZER LTD (GB) | 2007-07-18 | — | — | EP | claimed |
| EP-1558598-A1 | TRIAZOLE COMPOUNDS FOR THE TREATMENT OF DYSMENORRHOEA | Pfizer Limited (GB) | 2005-08-03 | — | — | EP | claimed |
| WO-2004037809-A1 | TRIAZOLE COMPOUNDS FOR THE TREATMENT OF DYSMENORRHOEA | PFIZER LIMITED (GB) | 2004-05-06 | — | — | WO | claimed |
| EP-1656183-B1 | TREATMENT OF MALE SEXUAL DYSFUNCTION | PFIZER LTD (GB) | 2007-12-05 | — | — | EP | disclosed |
| EP-1558598-B1 | TRIAZOLE COMPOUNDS FOR THE TREATMENT OF DYSMENORRHOEA | PFIZER LTD (GB) | 2007-07-18 | — | — | EP | disclosed |
| EP-1656183-A1 | TREATMENT OF MALE SEXUAL DYSFUNCTION | Pfizer Limited (GB) | 2006-05-17 | — | — | EP | disclosed |
| EP-1558598-A1 | TRIAZOLE COMPOUNDS FOR THE TREATMENT OF DYSMENORRHOEA | Pfizer Limited (GB) | 2005-08-03 | — | — | EP | disclosed |
| WO-2005006899-A1 | TREATMENT OF MALE SEXUAL DYSFUNCTION | PFIZER LIMITED (GB) | 2005-01-27 | — | — | WO | disclosed |
| WO-2004037809-A1 | TRIAZOLE COMPOUNDS FOR THE TREATMENT OF DYSMENORRHOEA | PFIZER LIMITED (GB) | 2004-05-06 | — | — | WO | disclosed |