Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5215077 | 1.00 | GPR119 (0.57) | GPR119TSHRALDH1A1LMNAKMT2A | |
| SCHEMBL21163171 | 0.80 | ALDH1A1 (0.65) | TSHRALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL5216077 | 0.80 | AVPR1A (0.58) | GPR119TSHRALDH1A1LMNAKMT2A | |
| SCHEMBL5847350 | 0.80 | AVPR1A (0.58) | GPR119TSHRALDH1A1LMNAKMT2A | |
| SCHEMBL5219564 | 0.79 | GPR119 (0.53) | GPR119MAPTGAATHRBSMN1; SMN2 | |
| SCHEMBL5215617 | 0.77 | GPR119 (0.51) | GPR119ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL5211613 | 0.76 | GPR119 (0.50) | GPR119MAPTGAATHRBSMN1; SMN2 | |
| SCHEMBL4955775 | 0.76 | ALDH1A1 (0.60) | TSHRALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL4955786 | 0.76 | ALDH1A1 (0.60) | TSHRALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL8357676 | 0.75 | GPR119 (0.59) | GPR119ALDH1A1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7084145-B2 | Triazole compounds useful in therapy | PFIZER INC. (US) | 2006-08-01 | — | — | US | disclosed |
| US-20040162278-A1 | Triazole compounds useful in therapy | PFIZER INC | 2004-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040162278-A1 | Triazole compounds useful in therapy | AVPR2, AVPR1B, AVPR1A | GPR119 284/4885TSHR 80/4885ALDH1A1 704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.