Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | SMO | Q99835 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5197401 | 0.91 | ALDH1A1 (0.39) | PRKCAMMP12EGLN1SCN9ACYP3A4 | |
| SCHEMBL5224331 | 0.90 | EGLN1 (0.35) | PRKCAMMP12EGLN1SCN9ACYP3A4 | |
| SCHEMBL5196861 | 0.90 | GRIN2B (0.39) | PRKCAMMP12EGLN1SCN9ACYP3A4 | |
| SCHEMBL5197903 | 0.90 | PRKCA (0.41) | PRKCAMMP12SCN9ACYP3A4CYP2C19 | |
| SCHEMBL5196756 | 0.90 | PRKCA (0.39) | PRKCAMMP12EGLN1SCN9ACYP3A4 | |
| SCHEMBL5219759 | 0.89 | TMEM97 (0.37) | PRKCAMMP12EGLN1SCN9ACYP3A4 | |
| SCHEMBL5197220 | 0.89 | HRH1 (0.41) | PRKCAMMP12EGLN1SCN9AHRH1 | |
| SCHEMBL5197342 | 0.89 | HPGD (0.41) | PRKCAMMP12EGLN1SCN9ANR1I2 | |
| SCHEMBL5257079 | 0.89 | BRD4 (0.37) | PRKCAMMP12EGLN1SCN9ACYP3A4 | |
| SCHEMBL5198225 | 0.89 | JAK2 (0.35) | PRKCAMMP12EGLN1SCN9ANR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844042-A1 | INDOLE DERIVATIVES FOR TREATING VIRAL INFECTIONS | GENELABS TECHNOLOGIES, INC. (US) | 2007-10-17 | — | — | EP | claimed |
| WO-2006076529-A1 | INDOLE DERIVATIVES FOR TREATING VIRAL INFECTIONS | GENELABS TECHNOLOGIES, INC. (US) | 2006-07-20 | — | — | WO | claimed |