⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2406026 | 0.89 | — | — | |
| SCHEMBL26154082 | 0.87 | — | — | |
| SCHEMBL1338682 | 0.83 | NPC1 (0.48) | — | |
| SCHEMBL15687874 | 0.80 | — | — | |
| SCHEMBL15688216 | 0.80 | — | — | |
| SCHEMBL15687872 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL18064601 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL18064602 | 0.80 | — | — | |
| SCHEMBL15687959 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL18064600 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1028940-B1 | PROCESS TO PRODUCE OXAZOLIDINONES | PHARMACIA & UPJOHN CO LLC (US) | 2007-04-18 | — | — | EP | disclosed |
| EP-1772453-A1 | Process to produce Oxazolidinones | Pharmacia & Upjohn Company LLC (US) | 2007-04-11 | — | — | EP | disclosed |
| EP-1328509-B1 | METHODS OF PRODUCING OXAZOLIDINONE COMPOUNDS | PHARMACIA & UPJOHN CO LLC (US) | 2006-03-22 | — | — | EP | disclosed |
| US-6998420-B2 | Oxazolidinone compounds | PHARMACIA & UPJOHN COMPANY (US) | 2006-02-14 | — | — | US | disclosed |
| US-6833453-B2 | As an example, manufacturing a 5-(tert-butylcarbamoyl)-amino-methyl-oxazolidinone by condensing a carbamate with a tert-butylcarbamoyl protected derivative of glycidylamine or a 3-amino-1-halopropanol | PHARMACIA & UPJOHN COMPANY | 2004-12-21 | — | — | US | disclosed |
| US-20040143131-A1 | in particular,manufacturing a 5-(tert-butylcarbamoyl)-aminomethyl-oxazolidinone by condensing a carbamate with a tert-butylcarbamoyl protected derivative of glycidylamine or 3-amino-1-halopropanol, intermediates | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
| US-6740754-B2 | CYCLIZATION OF CARBAMATE WITH SECONDARY ALCOHOL, EPOXIDE OR ESTER REACTANT | PHARMACIA & UPJOHN COMPANY | 2004-05-25 | — | — | US | disclosed |
| US-6716980-B2 | CYCLIZATION AND ACYLATION OF CARBAMATE | PHARMACIA & UPJOHN COMPANY | 2004-04-06 | — | — | US | disclosed |
| US-20040006238-A1 | Process to produce oxazolidinones | PHARMACIA & UPJOHN COMPANY | 2004-01-08 | — | — | US | disclosed |
| US-20030216572-A1 | PROCESS TO PRODUCE OXAZOLIDINONES | PHARMACIA & UPJOHN COMPANY | 2003-11-20 | — | — | US | disclosed |
| US-6492555-B2 | REACTION OF A CARBAMATE WITH EITHER A (S)-SECONDARY ALCOHOL OR (S)-EPOXIDE OR (S)-ESTER; BACTERICIDES | PHARMACIA & UPJOHN COMPANY | 2002-12-10 | — | — | US | disclosed |
| US-20020095054-A1 | Process to produce oxazolidinones | PHARMACIA & UPJOHN COMPANY | 2002-07-18 | — | — | US | disclosed |
| US-20020086900-A1 | Methods of producing oxazolidinone compounds | PERRAULT WILLIAM R (US) | 2002-07-04 | — | — | US | disclosed |
| US-6410788-B1 | BACTERICIDES; REACTING IMINE, CARBAMATE, ESTER, AMIDE AND EPOXIDE DERIVATIVES | PHARMACIA & UPJOHN COMPANY | 2002-06-25 | — | — | US | disclosed |
| WO-2002032857-A1 | METHODS OF PRODUCING OXAZOLIDINONE COMPOUNDS | PHARMACIA & UPJOHN COMPANY (US) | 2002-04-25 | — | — | WO | disclosed |
| US-6362334-B1 | OXAZOLIDINONE PHTHALAMIDE | PHARMACIA & UPJOHN COMPANY | 2002-03-26 | — | — | US | disclosed |
| US-20020032348-A1 | Process to produce oxazolidinones | PEARLMAN BRUCE ALLEN (US) | 2002-03-14 | — | — | US | disclosed |
| EP-1028940-A1 | PROCESS TO PRODUCE OXAZOLIDINONES | PHARMACIA & UPJOHN COMPANY (US) | 2000-08-23 | — | — | EP | disclosed |
| US-6107519-A | Process to produce oxazolidinones | PHARMACIA & UPJOHN COMPANY (US) | 2000-08-22 | — | — | US | disclosed |
| WO-1999024393-A1 | PROCESS TO PRODUCE OXAZOLIDINONES | PHARMACIA & UPJOHN COMPANY (US) | 1999-05-20 | — | — | WO | disclosed |