SCHEMBL1338682

SCHEMBL1338682

O=C(Nc1ccc(C2CNCCO2)c(F)c1)OCc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.48
ALDH1A1 P00352 1/20 0.48
TP53 P04637 1/20 0.48
MAPT P10636 1/20 0.48
TSHR P16473 1/20 0.48
RAB9A P51151 1/20 0.48
ATM Q13315 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
MGLL Q99685 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2406026 0.86
SCHEMBL28997912 0.83 KDM1A (0.57)
SCHEMBL5216740 0.83
SCHEMBL5204617 0.83
SCHEMBL26154082 0.82
SCHEMBL8347802 0.80 MGLL (0.47) NPC1ALDH1A1TP53MAPTTSHR
SCHEMBL4688897 0.79 MGLL (0.46) NPC1ALDH1A1TP53MAPTTSHR
SCHEMBL14197111 0.76 TP53 (0.53) NPC1ALDH1A1TP53MAPTTSHR
SCHEMBL4882624 0.76 TP53 (0.53) NPC1ALDH1A1TP53MAPTTSHR
SCHEMBL8348584 0.76 MGLL (0.49) NPC1ALDH1A1TP53MAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107540625-B Preparation method of linezolid 正大天晴药业集团股份有限公司 2021-06-25 CN claimed
CN-121698825-A Synthesis method of high-purity N-carbobenzoxy-3-fluoro-4-morpholinylaniline 河北国龙制药有限公司 2026-03-20 CN disclosed
CN-121698825-A Synthesis method of high-purity N-carbobenzoxy-3-fluoro-4-morpholinylaniline 河北国龙制药有限公司 2026-03-20 CN disclosed
CN-113045509-B Industrial production method of linezolid 上海翰森生物医药科技有限公司 2021-10-22 CN disclosed
CN-113045509-A Industrial production method of linezolid 上海翰森生物医药科技有限公司 2021-06-29 CN disclosed
CN-107540625-B Preparation method of linezolid 正大天晴药业集团股份有限公司 2021-06-25 CN disclosed
CN-107540625-B Preparation method of linezolid 正大天晴药业集团股份有限公司 2021-06-25 CN disclosed
CN-107698533-B Method for preparing linezolid 浙江海翔川南药业有限公司 2021-03-26 CN disclosed
US-9012631-B2 1,3-oxazolidine-2-one-like compound, preparation method and uses thereof YABANG PHARMACEUTICAL CO., LTD (CN) 2015-04-21 US disclosed
CN-102977056-B Synthesis method of N-carbobenzoxy-3-fluoro-4-morpholinylaniline SHENZHEN MAIN LUCK PHARMACEUTICALS INC 2014-11-26 CN disclosed
US-8038543-B2 Golf swing training device CAPESIUS DEAN C 2011-10-18 US disclosed
WO-2011114210-A2 PROCESSES FOR THE PREPARATION OF LINEZOLID JUBILANT LIFE SCIENCES LIMITED (IN) 2011-09-22 WO disclosed
WO-2011077310-A1 PROCESS FOR THE PREPARATION OF LINEZOLID ALEMBIC LIMITED (IN) 2011-06-30 WO disclosed
EP-1380121-B1 PROCESS TO PREPARE OXAZOLIDINONES PHARMACIA & UPJOHN CO LLC (US) 2007-09-26 EP disclosed
US-7087784-B2 Process to prepare oxazolidinones PHARMACIA & UPJOHN (US) 2006-08-08 US disclosed
US-6887995-B2 Process to prepare oxazolidinones PHARMACIA & UPJOHN COMPANY (US) 2005-05-03 US disclosed
US-20040220407-A1 Process to prepare oxazolidinones PERRAULT WILLIAM R 2004-11-04 US disclosed
EP-1380121-A2 PROCESS TO PREPARE OXAZOLIDINONES PHARMACIA & UPJOHN COMPANY (US) 2004-01-14 EP disclosed
US-20020169312-A1 Process to prepare oxazolidinones PHARMACIA & UPJOHN COMPANY 2002-11-14 US disclosed
WO-2002085849-A2 PROCESS TO PREPARE OXAZOLIDINONES PHARMACIA & UPJOHN COMPANY (US) 2002-10-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040220407-A1 Process to prepare oxazolidinones CYP3A5, OXA1L, CYP3A4 NPC1 4106/4885ALDH1A1 188/4885TP53 4526/4885
US-20020169312-A1 Process to prepare oxazolidinones CYP3A5, OXA1L, CYP3A4 NPC1 4106/4885ALDH1A1 188/4885TP53 4526/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.