Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 7/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAK | O14976 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL4481380 | 0.99 | FYN (0.38) | FYNTNFSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL4463735 | 0.86 | RXFP1 (0.39) | FYNSMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL2678945 | 0.83 | FYN (0.43) | FYNTNFSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL4475112 | 0.82 | CHRNA7 (0.37) | KDM1A | |
| SCHEMBL4461401 | 0.81 | ALOX5AP (0.31) | KDM1A | |
| SCHEMBL4465250 | 0.81 | KDM1A (0.40) | SMN1; SMN2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4470449 | 0.80 | SLC6A2 (0.38) | FYNKDM4EALDH1A1KDM1ACYP2D6 | |
| SCHEMBL4463819 | 0.79 | HSD11B1 (0.38) | — | |
| SCHEMBL5223011 | 0.79 | FYN (0.40) | FYNTNFSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL2678759 | 0.79 | FYN (0.42) | FYNTNFSMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465893-B1 | DERIVATIVES OF 5-(PYRIDIN-3-YL)-1-AZABICYCLO (3.2.1) OCTANE, THE PREPARATION THEREOF AND THE APPLICATION OF SAME IN THERAPEUTICS | SANOFI AVENTIS (FR) | 2007-02-28 | — | — | EP | claimed |