Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL361599 | 0.79 | DDB1 (0.48) | DDB1CRBNIGF1RALOX15TP53 | |
| SCHEMBL9149653 | 0.78 | CYP19A1 (0.62) | DDB1CRBNIGF1RALOX15TP53 | |
| SCHEMBL11577018 | 0.75 | MAPT (0.56) | KMT2ALMNACYP1A2MAPTMEN1 | |
| SCHEMBL11577013 | 0.75 | MAPT (0.56) | KMT2ALMNACYP1A2MAPTMEN1 | |
| SCHEMBL3438464 | 0.75 | ALDH1A1 (0.49) | DDB1CRBNIGF1RALOX15TP53 | |
| SCHEMBL3438466 | 0.75 | ALDH1A1 (0.49) | DDB1CRBNIGF1RALOX15TP53 | |
| SCHEMBL16179411 | 0.74 | TP53 (0.62) | DDB1CRBNIGF1RALOX15TP53 | |
| SCHEMBL6762506 | 0.74 | TP53 (0.62) | DDB1CRBNIGF1RALOX15TP53 | |
| SCHEMBL15874652 | 0.73 | SLC18A3 (0.51) | DDB1CRBNIGF1RALOX15TP53 | |
| SCHEMBL190786 | 0.73 | SLC18A3 (0.51) | DDB1CRBNIGF1RALOX15TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202978-B1 | ISOXAZOLYL- AND ISOXAZOLINYL-SUBSTITUTED BENZOYLCYCLOHEXANEDIONES, PRODUCTION METHOD AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AG (DE) | 2007-10-31 | — | — | EP | disclosed |
| EP-1202978-A1 | ISOXAZOLYL- AND ISOXAZOLINYL-SUBSTITUTED BENZOYLCYCLOHEXANEDIONES, PRODUCTION METHOD AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | Aventis CropScience GmbH (DE) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001007422-A1 | ISOXAZOLYL- AND ISOXAZOLINYL-SUBSTITUTED BENZOYLCYCLOHEXANEDIONES, PRODUCTION METHOD AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | AVENTIS CROPSCIENCE GMBH (DE) | 2001-02-01 | — | — | WO | disclosed |