Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 13/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | PRCP | P42785 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23123839 | 0.83 | CHRM1 (0.41) | EPHX1NAAAPRCPNAMPTEPHX2 | |
| SCHEMBL24176155 | 0.79 | EPHX1 (0.50) | EPHX1NAAAPRCPNAMPT | |
| SCHEMBL30359136 | 0.77 | GNAI3 (0.48) | EPHX1NAAAPRCPNAMPTEPHX2 | |
| SCHEMBL24700461 | 0.76 | CHRM1 (0.42) | EPHX1NAAAEPHX2 | |
| SCHEMBL24176160 | 0.74 | TDP1 (0.65) | EPHX1NAAANAMPT | |
| SCHEMBL4285086 | 0.74 | TDP1 (0.65) | EPHX1NAAANAMPT | |
| SCHEMBL28165171 | 0.74 | TDP1 (0.65) | EPHX1NAAANAMPT | |
| SCHEMBL10739048 | 0.74 | TDP1 (0.65) | EPHX1NAAANAMPT | |
| SCHEMBL10739485 | 0.74 | TDP1 (0.65) | EPHX1NAAANAMPT | |
| SCHEMBL28273729 | 0.74 | TDP1 (0.65) | EPHX1NAAANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786809-A2 | AMINOPIPERIDINE DERIVATIVES, PREPARATION THEREOF AND USE THEREOF AS MELANOCORTIN RECEPTOR AGONISTS | Sanofi-Aventis (FR) | 2007-05-23 | — | — | EP | claimed |
| WO-2006021656-A2 | AMINOPIPERIDINE DERIVATIVES, PREPARATION THEREOF AND USE THEREOF AS MELANOCORTIN RECEPTOR AGONISTS | SANOFI-AVENTIS (FR) | 2006-03-02 | — | — | WO | claimed |