Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.48 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.48 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 10/20 | 0.47 |
| ▸ | PRCP | P42785 | 2/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13265399 | 0.83 | KMT2A (0.47) | EPHX1 | |
| SCHEMBL25851700 | 0.77 | HTT (0.50) | EPHX1 | |
| SCHEMBL23123839 | 0.77 | CHRM1 (0.41) | EPHX1PRCPNAAANAMPTEPHX2 | |
| SCHEMBL25424421 | 0.77 | CHRNB2 (0.38) | — | |
| SCHEMBL23123303 | 0.77 | CHRM1 (0.44) | EPHX1NAAAEPHX2 | |
| SCHEMBL23123302 | 0.77 | CHRM1 (0.44) | EPHX1NAAAEPHX2 | |
| SCHEMBL5217491 | 0.77 | EPHX1 (0.50) | EPHX1PRCPNAAANAMPTEPHX2 | |
| SCHEMBL3241059 | 0.75 | L3MBTL1 (0.39) | GNAI3GNAO1GNAI1EPHX1PRCP | |
| SCHEMBL30417783 | 0.75 | GNAI3 (0.40) | GNAI3GNAO1GNAI1EPHX1PRCP | |
| SCHEMBL23123998 | 0.74 | NAMPT (0.49) | EPHX1NAAANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116057057-A | Conjugates of alpha 2-adrenoceptor subtype C (alpha-2C) antagonists and TASK1/3 channel blockers for the treatment of sleep apnea | 拜耳公司 | 2023-05-02 | — | — | CN | disclosed |