Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 5/20 | 1.00 |
| ▸ | MAPT | P10636 | 6/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.72 |
| ▸ | MEN1 | O00255 | 3/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.72 |
| ▸ | RECQL | P46063 | 1/20 | 0.72 |
| ▸ | BCL2 | P10415 | 5/20 | 0.71 |
| ▸ | BCL2L2 | Q92843 | 5/20 | 0.71 |
| ▸ | BAD | Q92934 | 5/20 | 0.71 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.70 |
| ▸ | MME | P08473 | 2/20 | 0.69 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.69 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | CRHBP | P24387 | 1/20 | 0.68 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | APAF1 | O14727 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3054451 | 0.87 | ADAMTS5 (0.77) | ADAMTS5MAPTKMT2AMEN1POLB | |
| SCHEMBL6888325 | 0.86 | ADAMTS5 (0.76) | ADAMTS5MAPTKMT2AMEN1POLB | |
| SCHEMBL6888323 | 0.86 | ADAMTS5 (0.76) | ADAMTS5MAPTKMT2AMEN1POLB | |
| SCHEMBL19430434 | 0.84 | MAPT (1.00) | ADAMTS5MAPTKMT2AMEN1POLB | |
| SCHEMBL13846498 | 0.83 | MAPT (0.87) | ADAMTS5MAPTKMT2AMEN1POLB | |
| SCHEMBL7149409 | 0.81 | ADAMTS5 (0.68) | ADAMTS5MAPTKMT2AMEN1POLB | |
| SCHEMBL245003 | 0.81 | ADAMTS5 (1.00) | ADAMTS5PTPN1 | |
| SCHEMBL186520 | 0.81 | ADAMTS5 (1.00) | ADAMTS5PTPN1 | |
| SCHEMBL3638794 | 0.80 | MAPT (0.82) | ADAMTS5MAPTKMT2AMEN1POLB | |
| SCHEMBL12678079 | 0.80 | MAPT (0.82) | ADAMTS5MAPTKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313471-B1 | BENZYLIDENE THIAZOLIDINEDIONES AND THEIR USE AS ANTIMYCOTIC AGENTS | UCB SA (BE) | 2007-04-11 | — | — | EP | disclosed |
| US-7105554-B2 | Benzylidene thiazolidinediones and their use as antimycotic agents | OXFORD GLYCOSCIENCES (UK) LTD. (GB) | 2006-09-12 | — | — | US | disclosed |
| US-20040006112-A1 | Benzylidene thiazolidinediones and their use as antimycotic agents | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2004-01-08 | — | — | US | disclosed |
| EP-1313471-A1 | BENZYLIDENE THIAZOLIDINEDIONES AND THEIR USE AS ANTIMYCOTIC AGENTS | Oxford GlycoSciences (UK) Limited (GB) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002017915-A1 | BENZYLIDENE THIAZOLIDINEDIONES AND THEIR USE AS ANTIMYCOTIC AGENTS | OXFORD GLYCOSCIENCES (UK) LIMITED (GB) | 2002-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006112-A1 | Benzylidene thiazolidinediones and their use as antimycotic agents | SLC5A2, OXSR1, SLC5A1 | ADAMTS5 4556/4885MAPT 4658/4885KMT2A 2718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.