Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4883360 | 0.90 | P2RX7 (0.57) | P2RX7 | |
| SCHEMBL5221250 | 0.80 | P2RX7 (0.56) | P2RX7 | |
| SCHEMBL4881090 | 0.80 | P2RX7 (0.70) | P2RX7 | |
| SCHEMBL8071731 | 0.76 | P2RX7 (0.65) | P2RX7 | |
| SCHEMBL4883520 | 0.75 | P2RX7 (0.53) | P2RX7 | |
| SCHEMBL5118323 | 0.75 | P2RX7 (0.75) | P2RX7 | |
| SCHEMBL7517360 | 0.74 | P2RX7 (0.72) | P2RX7 | |
| SCHEMBL7690936 | 0.73 | P2RX7 (0.73) | P2RX7 | |
| SCHEMBL4095273 | 0.73 | P2RX7 (0.56) | P2RX7 | |
| SCHEMBL8080894 | 0.73 | P2RX7 (0.56) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786786-A1 | ADAMANTYL DERIVATES AS P2X7 RECEPTOR ANTAGONISTS | AstraZeneca AB (SE) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006025783-A1 | ADAMANTYL DERIVATES AS P2X7 RECEPTOR ANTAGONISTS | ASTRAZENECA AB (SE) | 2006-03-09 | — | — | WO | disclosed |