Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14920208 | 0.92 | SLC18A2 (0.44) | SLC6A3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL5221088 | 0.85 | TACR1 (0.48) | — | |
| SCHEMBL27738717 | 0.81 | CHRM2 (0.41) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL4252028 | 0.81 | PDE4B (0.57) | SLC6A3SLC6A2SLC6A4PDE4B | |
| SCHEMBL3002077 | 0.81 | PDE4B (0.57) | SLC6A3SLC6A2SLC6A4PDE4B | |
| SCHEMBL4252019 | 0.81 | PDE4B (0.57) | SLC6A3SLC6A2SLC6A4PDE4B | |
| SCHEMBL3002073 | 0.81 | PDE4B (0.57) | SLC6A3SLC6A2SLC6A4PDE4B | |
| SCHEMBL18344984 | 0.76 | L3MBTL1 (0.39) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL14921678 | 0.76 | PDE4B (0.44) | SLC6A3PDE4B | |
| SCHEMBL18780282 | 0.76 | PDE4B (0.44) | SLC6A3PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765780-A1 | PIPERIDINE COMPOUND AND PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006004195-A1 | PIPERIDINE COMPOUND AND PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 2006-01-12 | — | — | WO | disclosed |