Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 12/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5218252 | 0.85 | SLC6A3 (0.42) | — | |
| SCHEMBL4252177 | 0.82 | TACR1 (0.51) | TACR1CYP2D6CYP2C9CYP3A4 | |
| SCHEMBL4252168 | 0.82 | TACR1 (0.51) | TACR1CYP2D6CYP2C9CYP3A4 | |
| SCHEMBL4252171 | 0.82 | TACR1 (0.51) | TACR1CYP2D6CYP2C9CYP3A4 | |
| SCHEMBL26402882 | 0.80 | PROKR1 (0.45) | OPRL1KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL14920208 | 0.79 | SLC18A2 (0.44) | KDM4EMEN1ALDH1A1KMT2APKM | |
| SCHEMBL18971977 | 0.79 | TACR1 (0.47) | TACR1CYP2D6CYP2C9CYP3A4PKM | |
| SCHEMBL22721969 | 0.77 | SIGMAR1 (0.43) | TACR1CYP2D6CYP2C9CYP3A4 | |
| SCHEMBL4405607 | 0.75 | SMN1; SMN2 (0.50) | TACR1CYP2D6CYP2C9CYP3A4 | |
| SCHEMBL5259400 | 0.75 | SMN1; SMN2 (0.50) | TACR1CYP2D6CYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765780-A1 | PIPERIDINE COMPOUND AND PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006004195-A1 | PIPERIDINE COMPOUND AND PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 2006-01-12 | — | — | WO | disclosed |