Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | FAP | Q12884 | 2/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Leucine SCHEMBL6882071 | 0.86 | SLC7A5 (0.53) | ANPEPERAP2LMNACYP1A2CYP2D6 | |
| SCHEMBL18920966 | 0.85 | METAP1 (0.44) | ANPEPERAP2LMNACYP1A2CYP2D6 | |
| SCHEMBL250459 | 0.85 | ALDH1A1 (0.50) | KDM4EPOLBEPHX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL122347 | 0.85 | ALDH1A1 (0.50) | KDM4EPOLBEPHX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL163395 | 0.85 | ALDH1A1 (0.50) | KDM4EPOLBEPHX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL173401 | 0.85 | ALDH1A1 (0.50) | KDM4EPOLBEPHX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL201078 | 0.85 | ALDH1A1 (0.50) | KDM4EPOLBEPHX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL159315 | 0.85 | ALDH1A1 (0.50) | KDM4EPOLBEPHX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28833359 | 0.85 | ALDH1A1 (0.50) | KDM4EPOLBEPHX1ALDH1A1SMN1; SMN2 | |
| Cyclohexylglycyl SCHEMBL1256626 | 0.85 | DPP4 (0.42) | ANPEPERAP2KDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836201-A1 | PYRROLIDINE INHIBITORS OF IAP | Genentech, Inc. (US) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006069063-A1 | PYRROLIDINE INHIBITORS OF IAP | GENENTECH, INC. (US) | 2006-06-29 | — | — | WO | disclosed |