Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.53 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 2/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.37 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Leucine SCHEMBL7414158 | 0.98 | SLC7A5 (0.55) | SLC7A5SLC1A3SLC1A2GRIK1METAP1 | |
| Alanine SCHEMBL5219005 | 0.86 | ANPEP (0.44) | METAP1ANPEPERAP2EPHX1LMNA | |
| SCHEMBL18920966 | 0.85 | METAP1 (0.44) | SLC1A3SLC1A2GRIK1METAP1ANPEP | |
| Leucine SCHEMBL3724834 | 0.84 | SLC7A5 (0.60) | SLC7A5SLC1A3SLC1A2GRIK1EPHX1 | |
| Leucine SCHEMBL3724837 | 0.84 | SLC7A5 (0.60) | SLC7A5SLC1A3SLC1A2GRIK1EPHX1 | |
| Asparagine SCHEMBL6136838 | 0.84 | GRIK1 (0.43) | GRIK1METAP1ANPEPERAP2DPP7 | |
| Asparagine SCHEMBL6136836 | 0.84 | GRIK1 (0.43) | GRIK1METAP1ANPEPERAP2DPP7 | |
| Homoserine SCHEMBL9124592 | 0.81 | METAP1 (0.40) | SLC1A3SLC1A2GRIK1METAP1ANPEP | |
| Leucine SCHEMBL6369626 | 0.81 | SLC7A5 (0.55) | SLC7A5SLC1A3SLC1A2GRIK1EPHX1 | |
| Leucine SCHEMBL6369629 | 0.81 | SLC7A5 (0.55) | SLC7A5SLC1A3SLC1A2GRIK1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004103270-A2 | COMPOUNDS AND METHODS FOR TREATMENT OF THROMBOSIS | SUNTORY PHARMACEUTICAL RESEARCH LABORATORIES LLC (US) | 2004-12-02 | — | — | WO | disclosed |
| WO-2004089297-A2 | COMPOUNDS AND METHODS FOR TREATMENT OF THROMBOSIS | SUNTORY PHARMACEUTICAL RESEARCH LABORATORIES, LLC (US) | 2004-10-21 | — | — | WO | disclosed |