Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | SDHA | P31040 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CALML3 | P27482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | FAP | Q12884 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.31 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.31 |
| ▸ | RORC | P51449 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5216698 | 0.80 | MAOA (0.58) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL8359082 | 0.73 | MAOA (0.42) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL8359085 | 0.73 | MAOA (0.42) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7985431 | 0.72 | MAOA (0.40) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7805454 | 0.71 | MAOA (0.47) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7515727 | 0.71 | MAOB (0.44) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6164776 | 0.70 | MAOA (0.60) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL1176221 | 0.70 | MAOA (0.60) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6164308 | 0.70 | MAOA (0.60) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6164310 | 0.70 | MAOA (0.60) | MAOAMAOBPTGS1SDHALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1467992-B1 | ANTIMICROBIAL DIHYDROTHIAZINE AND DIHYDROTHIOPYRAN OXAZOLIDINONES | PHARMACIA & UPJOHN CO LLC (US) | 2007-08-08 | — | — | EP | disclosed |