Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.60 |
| ▸ | MAOB | P27338 | 3/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.60 |
| ▸ | SDHA | P31040 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | CALML3 | P27482 | 1/20 | 0.60 |
| ▸ | F10 | P00742 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6164776 | 1.00 | MAOA (0.60) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6164308 | 1.00 | MAOA (0.60) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL1176221 | 1.00 | MAOA (0.60) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6040265 | 0.92 | MAOA (0.52) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6040262 | 0.92 | MAOA (0.52) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6040393 | 0.92 | MAOA (0.52) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL8168992 | 0.91 | MAOB (0.50) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL8169547 | 0.91 | MAOB (0.50) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6966649 | 0.91 | MAOB (0.50) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL8168995 | 0.91 | MAOB (0.50) | MAOAMAOBPTGS1SDHALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6083967-A | ANTIMICROBIAL AGENTS; ASSAY FOR DETERMINING THE INHIBITORY ACTIVITY OF OXAZOLIDINONES TO HUMAN MONOAMINE OXIDASE | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-04 | — | — | US | claimed |
| EP-0984947-B1 | OXAZOLIDINONE ANTIBACTERIAL AGENTS HAVING A THIOCARBONYL FUNCTIONALITY | UPJOHN CO (US) | 2005-04-20 | — | — | EP | disclosed |
| US-6537986-B2 | With thiourea, thioamide, or dithiocarbamate functionality; (S)-N-(((3-(3-fluoro-4-morpholinyl)phenyl)-2-oxo-5 -oxazolidinyl)methyl)thioacetamide for example; treats multiple-resistant staphylococci | PHARMACIA & UPJOHN COMPANY | 2003-03-25 | — | — | US | disclosed |
| US-6362189-B1 | GRAMNEGATIVE, GRAMPOSITIVE BACTERIA | PHARMACIA AND UPJOHN COMPANY | 2002-03-26 | — | — | US | disclosed |
| US-20020016323-A1 | Oxazolidinone antibacterial agents having a thiocarbonyl functionality | PHARMACIA & UPJOHN COMPANY | 2002-02-07 | — | — | US | disclosed |
| US-6342513-B1 | THIOCARBONYLAMIDES ON OXAZO-, ISOOXAZOLE OR FURANONE RINGS FOR USE AS BACTERICIDES | PHARMACIA AND UPJOHN COMPANY | 2002-01-29 | — | — | US | disclosed |
| US-20010046987-A1 | Oxazolidinones having a sulfoximine functionality | PHARMACIA & UPJOHN COMPANY | 2001-11-29 | — | — | US | disclosed |
| US-20010041728-A1 | Oxazolidinone antibacterial agents having a thiocarbonyl functionality | HESTER JACKSON B (US) | 2001-11-15 | — | — | US | disclosed |
| US-6255304-B1 | AIDS THERAPY | PHARMACIA & UPJOHN COMPANY | 2001-07-03 | — | — | US | disclosed |
| US-6218413-B1 | Oxazolidinone antibacterial agents having a thiocarbonyl functionality | PHARMACIA & UPJOHN COMPANY | 2001-04-17 | — | — | US | disclosed |
| US-6083967-A | ANTIMICROBIAL AGENTS; ASSAY FOR DETERMINING THE INHIBITORY ACTIVITY OF OXAZOLIDINONES TO HUMAN MONOAMINE OXIDASE | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010041728-A1 | Oxazolidinone antibacterial agents having a thiocarbonyl functionality | OXA1L, MRPL21, TOP1 | MAOA 3306/4885MAOB 2998/4885PTGS1 436/4885 |
| US-20020016323-A1 | Oxazolidinone antibacterial agents having a thiocarbonyl functionality | OXA1L, MRPL21, TOP1 | MAOA 3306/4885MAOB 2998/4885PTGS1 436/4885 |
| US-20010046987-A1 | Oxazolidinones having a sulfoximine functionality | OXA1L, SULT1A1, SULT1E1 | MAOA 923/4885MAOB 726/4885PTGS1 311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.