Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5212651 | 0.85 | ATM (0.41) | ALDH1A1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL5212662 | 0.85 | ATM (0.41) | ALDH1A1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL5675509 | 0.85 | ALDH1A1 (0.42) | VDRALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL5675513 | 0.85 | ALDH1A1 (0.42) | VDRALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL6181231 | 0.84 | VDR (0.52) | VDRALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL5672551 | 0.81 | VDR (0.39) | VDRMEN1KMT2ANPSR1CYP1A2 | |
| SCHEMBL5673931 | 0.80 | ALDH1A1 (0.42) | VDRALDH1A1MAPTAGTR1AGTR2 | |
| SCHEMBL5673966 | 0.80 | S1PR1 (0.49) | VDRALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL6181320 | 0.80 | VDR (0.52) | VDRALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL5673979 | 0.80 | VDR (0.38) | VDRALDH1A1MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1142879-B1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | ASTELLAS PHARMA INC (JP) | 2007-10-10 | — | — | EP | disclosed |
| US-7060721-B1 | Imidazole compounds and medicinal use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2006-06-13 | — | — | US | disclosed |
| EP-1142879-A1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |