Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | USP10 | Q14694 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5222330 | 0.97 | ALDH1A1 (0.45) | ALDH1A1PKMVCAM1LMNACMA1 | |
| SCHEMBL5218309 | 0.88 | VCAM1 (0.42) | ALDH1A1PKMVCAM1LMNACMA1 | |
| SCHEMBL27649978 | 0.86 | ALDH1A1 (0.40) | ALDH1A1PKMVCAM1LMNACMA1 | |
| SCHEMBL5220531 | 0.85 | VCAM1 (0.43) | ALDH1A1PKMVCAM1LMNACMA1 | |
| SCHEMBL27629953 | 0.85 | ALDH1A1 (0.41) | ALDH1A1PKMVCAM1LMNACMA1 | |
| SCHEMBL5225589 | 0.79 | ALDH1A1 (0.49) | ALDH1A1VCAM1LMNAMAPTPOLB | |
| SCHEMBL13326134 | 0.75 | HPGD (0.47) | ALDH1A1LMNAMAPTKDM4EHPGD | |
| SCHEMBL5224471 | 0.74 | POLB (0.47) | ALDH1A1LMNAMAPTHPGDPOLB | |
| SCHEMBL989006 | 0.74 | VCAM1 (0.56) | ALDH1A1PKMVCAM1LMNAMAPT | |
| SCHEMBL1479464 | 0.74 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567488-B1 | HYDROXYETHYLAMINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | GLAXO GROUP LTD (GB) | 2007-02-21 | — | — | EP | disclosed |