Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | ACP1 | P24666 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4460733 | 0.93 | KDR (0.33) | KDRKDM4CACP1ALOX5AP | |
| SCHEMBL4463296 | 0.77 | HSD11B1 (0.40) | HSD11B1 | |
| Bromide SCHEMBL4471147 | 0.76 | HSD11B1 (0.39) | HSD11B1 | |
| SCHEMBL1483313 | 0.75 | ROCK1 (0.36) | PARP1 | |
| SCHEMBL2820219 | 0.75 | PBRM1 (0.34) | ACP1 | |
| Hydrochloric Acid SCHEMBL1484299 | 0.74 | ROCK1 (0.35) | PARP1 | |
| SCHEMBL2678244 | 0.74 | HSD11B1 (0.41) | HSD11B1 | |
| SCHEMBL1483304 | 0.74 | — | — | |
| SCHEMBL5221717 | 0.73 | CYP2A6 (0.47) | ALOX5AP | |
| Bromide SCHEMBL4468359 | 0.72 | CYP2A6 (0.46) | ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465893-B1 | DERIVATIVES OF 5-(PYRIDIN-3-YL)-1-AZABICYCLO (3.2.1) OCTANE, THE PREPARATION THEREOF AND THE APPLICATION OF SAME IN THERAPEUTICS | SANOFI AVENTIS (FR) | 2007-02-28 | — | — | EP | claimed |