Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.34 |
| ▸ | ACP1 | P24666 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4460733 | 0.81 | KDR (0.33) | PBRM1ACP1 | |
| SCHEMBL668390 | 0.79 | ACHE (0.36) | — | |
| SCHEMBL2818737 | 0.79 | ROCK1 (0.33) | — | |
| SCHEMBL2820232 | 0.76 | — | — | |
| SCHEMBL2823342 | 0.76 | HSD11B1 (0.36) | CHRNB4CHRNA3 | |
| SCHEMBL2846380 | 0.76 | IL4I1 (0.38) | ACP1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| Oxalic Acid SCHEMBL5220445 | 0.75 | KDR (0.38) | ACP1 | |
| Hydrochloric Acid SCHEMBL668528 | 0.75 | — | — | |
| SCHEMBL2823249 | 0.75 | ALDH1A1 (0.39) | PBRM1 | |
| Hydrochloric Acid SCHEMBL2821800 | 0.75 | HSD11B1 (0.35) | CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1922320-B1 | DERIVATIVES OF 5-PYRIDAZINYL-1-AZABICYCLO[3.2.1]OCTANE, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | SANOFI AVENTIS (FR) | 2010-10-27 | — | — | EP | claimed |