SCHEMBL5220967

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5215869	0.81	AHR (0.48)	AHRMAPTALDH1A1KDM4EGAA
	SCHEMBL5217889	0.79	MAPT (0.47)	AHRMAPTALDH1A1KDM4EGAA
	SCHEMBL5222461	0.77	AHR (0.42)	AHRMAPTALDH1A1KDM4EGAA
	SCHEMBL5215256	0.77	HSD17B10 (0.52)	ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2
	SCHEMBL5221390	0.76	MIF (0.47)	AHRMAPTALDH1A1KDM4EGAA
	SCHEMBL5215762	0.76	AHR (0.49)	AHRMAPTALDH1A1KDM4EGAA
	SCHEMBL14380692	0.76	MIF (0.47)	AHRMAPTALDH1A1KDM4EGAA
	SCHEMBL5215780	0.76	MAPT (0.42)	AHRMAPTALDH1A1KDM4EGAA
	SCHEMBL5219303	0.76	GRM4 (0.44)	AHRMAPTALDH1A1KDM4EGAA
	SCHEMBL5217836	0.76	ALDH1A1 (0.50)	MAPTALDH1A1KDM4ENPC1HCRTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.