Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | PGK1 | P00558 | 1/20 | 0.42 |
| ▸ | PGK2 | P07205 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | XPO1 | O14980 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL107119 | 0.87 | RAPGEF4 (0.56) | RAPGEF4IDO1PGK1PGK2MAPT | |
| SCHEMBL22783308 | 0.82 | RAPGEF4 (0.44) | RAPGEF4IDO1PGK1PGK2MAPT | |
| SCHEMBL130017 | 0.82 | RAPGEF4 (0.50) | RAPGEF4PGK1PGK2MAPTCES2 | |
| SCHEMBL26945216 | 0.81 | RAPGEF4 (0.47) | RAPGEF4IDO1PGK1PGK2MAPT | |
| SCHEMBL15978710 | 0.80 | RAPGEF4 (0.43) | RAPGEF4IDO1PGK1PGK2MAPT | |
| SCHEMBL823297 | 0.80 | IDO1 (0.44) | RAPGEF4IDO1GRIN2BNOS3NOS1 | |
| Ethylamine SCHEMBL8079279 | 0.79 | TAAR1 (0.52) | RAPGEF4IDO1NOS3NOS1TAAR1 | |
| Hydrochloric Acid SCHEMBL18740973 | 0.79 | IDO1 (0.46) | RAPGEF4IDO1GRIN2BNOS3NOS1 | |
| SCHEMBL12722384 | 0.78 | RAPGEF4 (0.48) | RAPGEF4IDO1PGK1PGK2MAPT | |
| SCHEMBL3439602 | 0.78 | RAPGEF4 (0.48) | RAPGEF4IDO1PGK1PGK2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765780-A1 | PIPERIDINE COMPOUND AND PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006004195-A1 | PIPERIDINE COMPOUND AND PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 2006-01-12 | — | — | WO | disclosed |