Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7077095 | 0.99 | KMT2A (0.46) | KMT2ATGFBR1ADORA2AADORA1ALDH1A1 | |
| SCHEMBL5216317 | 0.95 | KMT2A (0.43) | KMT2ATGFBR1ADORA2AADORA1EPAS1 | |
| SCHEMBL5219243 | 0.87 | KMT2A (0.38) | KMT2ATGFBR1ADORA2AADORA1ALDH1A1 | |
| SCHEMBL8475741 | 0.86 | ADORA2A (0.46) | KMT2ATGFBR1ADORA2AADORA1ALDH1A1 | |
| SCHEMBL5227796 | 0.81 | KMT2A (0.51) | KMT2ATGFBR1ADORA2AADORA1ALDH1A1 | |
| SCHEMBL7252609 | 0.80 | KMT2A (0.46) | KMT2ATGFBR1ADORA2AADORA1ALDH1A1 | |
| SCHEMBL5223076 | 0.79 | KMT2A (0.44) | KMT2ATGFBR1ADORA2AADORA1ALDH1A1 | |
| SCHEMBL6281244 | 0.79 | ADORA2A (0.50) | KMT2ATGFBR1ADORA2AADORA1ALDH1A1 | |
| SCHEMBL8932322 | 0.79 | KMT2A (0.44) | KMT2ATGFBR1ADORA2AADORA1ALDH1A1 | |
| SCHEMBL7245294 | 0.79 | SCN9A (0.40) | KMT2AADORA2AADORA1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458685-B1 | SUBSTITUTED PHENYL DERIVATIVES | BAYER CROPSCIENCE GMBH (DE) | 2007-05-02 | — | — | EP | disclosed |
| EP-1458685-A2 | SUBSTITUTED PHENYL DERIVATIVES | Bayer CropScience GmbH (DE) | 2004-09-22 | — | — | EP | disclosed |
| US-6750222-B2 | WITHOUT THE COMMON DISADVANTAGES, SUCH AS, FOR EXAMPLE, LONG PERSISTENCY, INSUFFICIENT SELECTIVITY IN IMPORTANT CROPS OF USEFUL PLANTS OR LACK OF ACTIVITY AGAINST HARMFUL PLANTS | BAYER CROPSCIENCE GMBH (DE) | 2004-06-15 | — | — | US | disclosed |
| US-20030228982-A1 | Substituted phenyl derivatives | BAYER CROPSCIENCE AG (DE) | 2003-12-11 | — | — | US | disclosed |
| WO-2003051846-A2 | SUBSTITUTED PHENYL DERIVATIVES | BAYER CROPSCIENCE GMBH (DE) | 2003-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030228982-A1 | Substituted phenyl derivatives | CYP1B1, DDT, CYP4X1 | KMT2A 792/4885TGFBR1 122/4885ADORA2A 1536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.