Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5221402 | 0.79 | KMT2A (0.47) | KMT2ATGFBR1ALDH1A1ADORA2AADORA1 | |
| SCHEMBL5227796 | 0.78 | KMT2A (0.51) | KMT2ATGFBR1ALDH1A1ADORA2AADORA1 | |
| SCHEMBL7077095 | 0.78 | KMT2A (0.46) | KMT2ATGFBR1ALDH1A1ADORA2AADORA1 | |
| SCHEMBL6281244 | 0.76 | ADORA2A (0.50) | KMT2ATGFBR1ALDH1A1ADORA2AADORA1 | |
| SCHEMBL5216317 | 0.75 | KMT2A (0.43) | KMT2ATGFBR1ADORA2AADORA1 | |
| SCHEMBL6532552 | 0.74 | ADORA2A (0.52) | KMT2ATGFBR1ALDH1A1ADORA2AADORA1 | |
| SCHEMBL9234287 | 0.74 | ADORA2A (0.42) | KMT2ATGFBR1ALDH1A1ADORA2AADORA1 | |
| SCHEMBL9289417 | 0.73 | ADORA2A (0.41) | KMT2ATGFBR1ALDH1A1ADORA2AADORA1 | |
| SCHEMBL15941810 | 0.72 | ALDH1A1 (0.52) | KMT2ATGFBR1ALDH1A1ADORA2AADORA1 | |
| SCHEMBL17732 | 0.71 | KDM4E (0.50) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458685-B1 | SUBSTITUTED PHENYL DERIVATIVES | BAYER CROPSCIENCE GMBH (DE) | 2007-05-02 | — | — | EP | disclosed |
| EP-1458685-A2 | SUBSTITUTED PHENYL DERIVATIVES | Bayer CropScience GmbH (DE) | 2004-09-22 | — | — | EP | disclosed |
| US-6750222-B2 | WITHOUT THE COMMON DISADVANTAGES, SUCH AS, FOR EXAMPLE, LONG PERSISTENCY, INSUFFICIENT SELECTIVITY IN IMPORTANT CROPS OF USEFUL PLANTS OR LACK OF ACTIVITY AGAINST HARMFUL PLANTS | BAYER CROPSCIENCE GMBH (DE) | 2004-06-15 | — | — | US | disclosed |
| US-20030228982-A1 | Substituted phenyl derivatives | BAYER CROPSCIENCE AG (DE) | 2003-12-11 | — | — | US | disclosed |
| WO-2003051846-A2 | SUBSTITUTED PHENYL DERIVATIVES | BAYER CROPSCIENCE GMBH (DE) | 2003-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030228982-A1 | Substituted phenyl derivatives | CYP1B1, DDT, CYP4X1 | KMT2A 792/4885TGFBR1 122/4885ALDH1A1 98/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.