SCHEMBL522156

SCHEMBL522156

C=C(CN)C(=O)NC(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.38
ALDH1A1 P00352 4/20 0.35
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
MMP1 P03956 1/20 0.33
MMP2 P08253 1/20 0.33
MMP9 P14780 1/20 0.33
MMP8 P22894 1/20 0.33
CA9 Q16790 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
FAAH O00519 1/20 0.32
MAPK1 P28482 1/20 0.32
GAA P10253 2/20 0.32
LMNA P02545 3/20 0.31
TGFBR1 P36897 1/20 0.31
CYP3A4 P08684 1/20 0.31
NFKB1 P19838 1/20 0.31
ADRA1A P35348 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25762110 0.79 TSHR (0.39) TSHRALDH1A1CA12CA1CA2
SCHEMBL8643965 0.79 TSHR (0.39) TSHRALDH1A1CA12CA1CA2
SCHEMBL25762106 0.77 TSHR (0.38) TSHRALDH1A1CA12CA1CA2
SCHEMBL6823681 0.76 TSHR (0.37) TSHRALDH1A1CA12CA1CA2
SCHEMBL24091493 0.76 TSHR (0.37) TSHRALDH1A1CA12CA1CA2
SCHEMBL14334873 0.74 ALDH1A1 (0.38) TSHRALDH1A1CA12CA1CA2
SCHEMBL9319960 0.74 EGFR (0.39) TSHRALDH1A1CA12CA1CA2
SCHEMBL28290138 0.74 TSHR (0.45) TSHRALDH1A1CA12CA1CA2
SCHEMBL6566443 0.73
SCHEMBL12684520 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0894099-A1 POLYMERIZABLE COMPOSITIONS COMPRISING A URETHANE OLIGOMER AS A CROSSLINKING AGENT, POLYMERS AND HYDRATED POLYMERS OBTAINED USING THESE COMPOSITIONS, AND FINISHED AND SEMI-FINISHED PRODUCTS MANUFACTURED USING THESE POLYMERS ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 1999-02-03 EP claimed
WO-1998036006-A1 POLYMERIZABLE COMPOSITIONS COMPRISING A URETHANE OLIGOMER AS A CROSSLINKING AGENT, POLYMERS AND HYDRATED POLYMERS OBTAINED USING THESE COMPOSITIONS, AND FINISHED AND SEMI-FINISHED PRODUCTS MANUFACTURED USING THESE POLYMERS ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 1998-08-20 WO claimed
US-9186441-B2 Surface treating agent, filtering material for filter, and blood treatment filter TERUMO KABUSHIKI KAISHA (JP) 2015-11-17 US disclosed
EP-2415490-A1 SURFACE-TREATING AGENT, FILTERING MATERIAL FOR FILTER, AND BLOOD TREATMENT FILTER Terumo Kabushiki Kaisha (JP) 2012-02-08 EP disclosed
US-20120024779-A1 SURFACE TREATING AGENT, FILTERING MATERIAL FOR FILTER, AND BLOOD TREATMENT FILTER TERUMO KABUSHIKI KAISHA (JP) 2012-02-02 US disclosed
US-4647606-A Blend of rapid set asphaltic emulsion with slow set asphalt emulsion OWENS-CORNING FIBERGLAS CORPORATION (US) 1987-03-03 US disclosed
US-4547225-A Additives for hot mix asphalt OWENS-CORNING FIBERGLAS CORPORATION (US) 1985-10-15 US disclosed
EP-0082056-B1 CATIONIC ACRYLAMIDE AND RUBBER MODIFIED ASPHALTS OWENS-CORNING FIBERGLAS CORPORATION (US) 1985-05-22 EP disclosed
US-4456633-A Chip seal technique employing blends of asphaltic emulsions OWENS-CORNING FIBERGLAS CORPORATION (US) 1984-06-26 US disclosed
US-4436864-A Aqueous emulsions of acrylamide and rubber modified asphalts OWENS-CORNING FIBERGLAS CORPORATION (US) 1984-03-13 US disclosed
US-4436767-A Slurry seal method using acrylamide and rubber modified asphaltic emulsion OWENS-CORNING FIBERGLAS CORPORATION (US) 1984-03-13 US disclosed
US-4419489-A Easily emulsifiable acrylamide and rubber modified asphalts OWENS-CORNING FIBERGLAS CORPORATION (US) 1983-12-06 US disclosed
US-4394481-A Cationic arcylamide and rubber modified asphalts OWENS-CORNING FIBERGLAS CORPORATION (US) 1983-07-19 US disclosed
WO-1983002115-A1 CATIONIC ACRYLAMIDE AND RUBBER MODIFIED ASPHALTS OWENS CORNING FIBERGLASS CORP (US) 1983-06-23 WO disclosed
EP-0082056-A1 Cationic acrylamide and rubber modified asphalts OWENS-CORNING FIBERGLAS CORPORATION (US) 1983-06-22 EP disclosed
US-4383081-A Cationic acrylamide chemically modified asphalts OWENS-CORNING FIBERGLAS CORPORATION (US) 1983-05-10 US disclosed