Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9319967 | 0.82 | ALDH1A1 (0.35) | TSHRALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL2187184 | 0.76 | EGFR (0.42) | EGFRPAX8 | |
| SCHEMBL8643965 | 0.76 | TSHR (0.39) | TSHRALDH1A1MEN1KMT2ACA12 | |
| SCHEMBL25762110 | 0.76 | TSHR (0.39) | TSHRALDH1A1MEN1KMT2ACA12 | |
| SCHEMBL25762106 | 0.74 | TSHR (0.38) | TSHRALDH1A1MEN1KMT2ACA12 | |
| SCHEMBL522156 | 0.74 | TSHR (0.38) | TSHRALDH1A1MEN1KMT2ACA12 | |
| SCHEMBL20225372 | 0.73 | ALDH1A1 (0.33) | TSHRALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL25588904 | 0.73 | ALDH1A1 (0.33) | TSHRALDH1A1GAA | |
| SCHEMBL18756716 | 0.73 | TSHR (0.31) | TSHR | |
| SCHEMBL9319824 | 0.73 | TSHR (0.41) | TSHRALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428970-B1 | Process for preparing aqueous solutions or suspensions of quaternization products of tertiary aminoalkylesters or tertiary aminoalkylamides of acrylic or methacrylic acid, for instance of dimethylaminoethyl-acrylate-methochloride | BASF AG (DE) | 1994-01-19 | — | — | EP | disclosed |
| US-4647606-A | Blend of rapid set asphaltic emulsion with slow set asphalt emulsion | OWENS-CORNING FIBERGLAS CORPORATION (US) | 1987-03-03 | — | — | US | disclosed |
| EP-0113038-B1 | PROCESS FOR PREPARING CONCENTRATED AQUEOUS SOLUTIONS OF QUATERNIZED PRODUCTS FROM TERTIARY AMINO ALKYL ESTERS OR AMIDES OF ACRYLIC OR METHACRYLIC ACIDS | BASF Aktiengesellschaft (DE) | 1986-09-10 | — | — | EP | disclosed |
| US-4547225-A | Additives for hot mix asphalt | OWENS-CORNING FIBERGLAS CORPORATION (US) | 1985-10-15 | — | — | US | disclosed |
| US-4520210-A | ALKYLATION IN WATER SOLUBLE KETONE THEN SEPARATION | BASF AKTIENGESELLSCHAFT (DE) | 1985-05-28 | — | — | US | disclosed |
| EP-0082056-B1 | CATIONIC ACRYLAMIDE AND RUBBER MODIFIED ASPHALTS | OWENS-CORNING FIBERGLAS CORPORATION (US) | 1985-05-22 | — | — | EP | disclosed |
| EP-0113038-A2 | Process for preparing concentrated aqueous solutions of quaternized products from tertiary amino alkyl esters or amides of acrylic or methacrylic acids | BASF Aktiengesellschaft (DE) | 1984-07-11 | — | — | EP | disclosed |
| US-4456633-A | Chip seal technique employing blends of asphaltic emulsions | OWENS-CORNING FIBERGLAS CORPORATION (US) | 1984-06-26 | — | — | US | disclosed |
| US-4436864-A | Aqueous emulsions of acrylamide and rubber modified asphalts | OWENS-CORNING FIBERGLAS CORPORATION (US) | 1984-03-13 | — | — | US | disclosed |
| US-4436767-A | Slurry seal method using acrylamide and rubber modified asphaltic emulsion | OWENS-CORNING FIBERGLAS CORPORATION (US) | 1984-03-13 | — | — | US | disclosed |
| US-4419489-A | Easily emulsifiable acrylamide and rubber modified asphalts | OWENS-CORNING FIBERGLAS CORPORATION (US) | 1983-12-06 | — | — | US | disclosed |
| US-4394481-A | Cationic arcylamide and rubber modified asphalts | OWENS-CORNING FIBERGLAS CORPORATION (US) | 1983-07-19 | — | — | US | disclosed |
| WO-1983002115-A1 | CATIONIC ACRYLAMIDE AND RUBBER MODIFIED ASPHALTS | OWENS CORNING FIBERGLASS CORP (US) | 1983-06-23 | — | — | WO | disclosed |
| EP-0082056-A1 | Cationic acrylamide and rubber modified asphalts | OWENS-CORNING FIBERGLAS CORPORATION (US) | 1983-06-22 | — | — | EP | disclosed |
| US-4383081-A | Cationic acrylamide chemically modified asphalts | OWENS-CORNING FIBERGLAS CORPORATION (US) | 1983-05-10 | — | — | US | disclosed |