Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TTK | P33981 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14949186 | 0.77 | CCR1 (0.54) | PDE10AKMOSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL30094777 | 0.74 | KMO (0.41) | PDE10AKMOSMN1; SMN2ALDH1A1 | |
| SCHEMBL1557065 | 0.74 | KMO (0.41) | PDE10AKMOSMN1; SMN2ALDH1A1 | |
| SCHEMBL1656606 | 0.74 | KMO (0.41) | PDE10AKMOSMN1; SMN2ALDH1A1TTK | |
| SCHEMBL14946750 | 0.72 | KMO (0.40) | PDE10AKMOSMN1; SMN2TTK | |
| SCHEMBL29454964 | 0.72 | KDM4E (0.44) | KMOSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL2897149 | 0.71 | KMO (0.39) | PDE10AKMOSMN1; SMN2 | |
| SCHEMBL5222321 | 0.68 | AOC3 (0.36) | SMN1; SMN2ALDH1A1KMT2ALMNA | |
| SCHEMBL6651069 | 0.68 | KMO (0.39) | PDE10AKMOSMN1; SMN2LMNA | |
| SCHEMBL3596359 | 0.67 | NPC1 (0.56) | KMOSMN1; SMN2HSD17B10ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799677-A1 | OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS | Ranbaxy Laboratories Limited (IN) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006038100-A1 | OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS | RANBAXY LABORATORIES LIMITED (IN) | 2006-04-13 | — | — | WO | disclosed |