Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 13/20 | 0.43 |
| ▸ | PPARD | Q03181 | 11/20 | 0.43 |
| ▸ | PPARG | P37231 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5222159 | 0.86 | KDM4E (0.44) | KDM4EMEN1HSP90AA1MAPTCRHBP | |
| SCHEMBL4877685 | 0.85 | PPARA (0.47) | KDM4EMEN1HSP90AA1MAPTCRHBP | |
| SCHEMBL14197497 | 0.82 | PPARA (0.47) | KDM4EMEN1HSP90AA1MAPTCRHBP | |
| SCHEMBL4867536 | 0.82 | PPARA (0.58) | PPARAPPARDPPARGNPC1ALDH1A1 | |
| SCHEMBL4877922 | 0.81 | ALDH1A1 (0.49) | KDM4EMEN1HSP90AA1MAPTCRHBP | |
| SCHEMBL4872840 | 0.79 | PPARA (0.58) | PPARAPPARDPPARGNPC1ALDH1A1 | |
| SCHEMBL14197488 | 0.76 | CNR1 (0.47) | MEN1MAPTKMT2APPARAPPARD | |
| SCHEMBL13334281 | 0.75 | PPARD (0.49) | PPARAPPARDPPARGFFAR1 | |
| SCHEMBL4878572 | 0.74 | PPARA (0.58) | MEN1MAPTKMT2APPARAPPARD | |
| SCHEMBL4878373 | 0.73 | PPARA (0.54) | MAPTPPARAPPARDPPARGESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1824484-A1 | DRUGS AND PRODRUGS USEFUL FOR THE TREATMENT OF ENERGY BALANCE IN RUMINANTS | Pfizer Products Incorporated (US) | 2007-08-29 | — | — | EP | disclosed |
| WO-2006054166-A1 | DRUGS AND PRODRUGS USEFUL FOR THE TREATMENT OF ENERGY BALANCE IN RUMINANTS | PFIZER PRODUCTS INC. (US) | 2006-05-26 | — | — | WO | disclosed |