Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14197485 | 0.97 | CNR1 (0.47) | CNR1MAPTALDH1A1HPGDLMNA | |
| SCHEMBL14197489 | 0.91 | CNR1 (0.51) | CNR1MAPTALDH1A1HPGDLMNA | |
| SCHEMBL4877685 | 0.91 | PPARA (0.47) | MAPTALDH1A1THRATHRBPPARA | |
| SCHEMBL14197497 | 0.87 | PPARA (0.47) | MAPTALDH1A1POLBL3MBTL1THRA | |
| SCHEMBL4875329 | 0.87 | CNR1 (0.51) | CNR1MAPTALDH1A1HPGDLMNA | |
| SCHEMBL4878373 | 0.85 | PPARA (0.54) | CNR1MAPTPOLBL3MBTL1PPARA | |
| SCHEMBL4867536 | 0.82 | PPARA (0.58) | ALDH1A1THRATHRBPPARANPC1 | |
| SCHEMBL4878572 | 0.82 | PPARA (0.58) | CNR1MAPTALDH1A1HPGDTHRA | |
| SCHEMBL4874167 | 0.81 | PPARA (0.54) | CNR1MAPTALDH1A1LMNAPOLB | |
| SCHEMBL4874131 | 0.80 | PPARA (0.55) | CNR1MAPTALDH1A1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096916-A1 | Drugs And Prodrugs Useful The Treatment Of Energy Balance In Ruminants | PFIZER INC. (US) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096916-A1 | Drugs And Prodrugs Useful The Treatment Of Energy Balance In Ruminants | ALPP, PIGS, GYS2 | CNR1 3749/4885MAPT 933/4885ALDH1A1 2168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.