Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 12/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5947204 | 0.93 | BCHE (0.59) | BCHESMN1; SMN2KDM4E | |
| SCHEMBL5223504 | 0.92 | BCHE (0.66) | BCHESMN1; SMN2KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL5947336 | 0.91 | BCHE (0.62) | BCHESMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL5947547 | 0.86 | BCHE (0.59) | BCHESMN1; SMN2KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL2533896 | 0.85 | BCHE (0.57) | BCHESMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL5947391 | 0.82 | BCHE (0.73) | BCHESMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL5175955 | 0.82 | BCHE (0.53) | BCHESMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL3957976 | 0.82 | BCHE (0.78) | BCHE | |
| SCHEMBL19532617 | 0.81 | BCHE (0.71) | BCHE | |
| SCHEMBL5947343 | 0.81 | KDM4E (0.68) | BCHESMN1; SMN2MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1379239-B1 | N-(2-ARYLETHYL) BENZYLAMINES AS ANTAGONISTS OF THE 5-HT6 RECEPTOR | LILLY CO ELI (US) | 2007-09-12 | — | — | EP | claimed |
| EP-1379239-B1 | N-(2-ARYLETHYL) BENZYLAMINES AS ANTAGONISTS OF THE 5-HT6 RECEPTOR | LILLY CO ELI (US) | 2007-09-12 | — | — | EP | disclosed |