Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.63 |
| ▸ | PPARA | Q07869 | 17/20 | 0.63 |
| ▸ | PPARD | Q03181 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5099400 | 0.78 | PPARG (1.00) | PPARGPPARAPPARD | |
| SCHEMBL6288254 | 0.78 | PPARG (0.75) | PPARGPPARAPPARD | |
| SCHEMBL5105744 | 0.75 | PPARG (0.67) | PPARGPPARAPPARD | |
| SCHEMBL14431770 | 0.74 | PPARG (0.58) | PPARGPPARAPPARD | |
| SCHEMBL5103119 | 0.74 | PPARG (0.68) | PPARGPPARAPPARD | |
| SCHEMBL6997196 | 0.73 | PPARG (0.57) | PPARGPPARAPPARD | |
| SCHEMBL14431366 | 0.73 | PPARG (0.59) | PPARGPPARAPPARD | |
| SCHEMBL5098184 | 0.73 | PPARA (0.68) | PPARGPPARAPPARD | |
| SCHEMBL5099360 | 0.72 | PPARG (0.55) | PPARGPPARAPPARD | |
| SCHEMBL4391342 | 0.71 | PPARG (0.59) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313715-B1 | OXAZOLYL-ARYLOXYACETIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | LILLY CO ELI (US) | 2007-08-01 | — | — | EP | disclosed |
| EP-1313715-A1 | OXAZOLYL-ARYLOXYACETIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018355-A1 | OXAZOLYL-ARYLOXYACETIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | ELI LILLY AND COMPANY (US) | 2002-03-07 | — | — | WO | disclosed |