SCHEMBL6288254

SCHEMBL6288254

Cc1oc(-c2ccccc2)nc1CCOc1ccc(-c2cccc(OC(C)C(=O)O)c2C)cc1

nearest known ligand 0.75

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARG P37231 20/20 0.75
PPARA Q07869 14/20 0.75
PPARD Q03181 3/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5099400 0.86 PPARG (1.00) PPARGPPARAPPARD
SCHEMBL6985706 0.80 PPARG (0.53) PPARGPPARAPPARD
SCHEMBL5103131 0.80 PPARG (0.82) PPARGPPARAPPARD
SCHEMBL5210093 0.79 PPARG (0.60) PPARGPPARAPPARD
SCHEMBL6989685 0.79 PPARG (0.76) PPARGPPARAPPARD
SCHEMBL4092245 0.78 PPARG (0.69) PPARGPPARAPPARD
SCHEMBL14431389 0.78 PPARG (0.79) PPARGPPARAPPARD
SCHEMBL5105206 0.78 PPARG (0.82) PPARGPPARAPPARD
SCHEMBL5222440 0.78 PPARG (0.63) PPARGPPARAPPARD
SCHEMBL8258850 0.77 PPARG (0.78) PPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040097590-A1 Oxazolyl-arylpropionic acid derivatives and their use as ppar agonists BROOKS DAWN ALISA (US) 2004-05-20 US claimed
US-6930120-B2 Oxazolyl-arylproplonic acid derivatives and their use as ppar agonists ELI LILLY AND COMPANY (US) 2005-08-16 US disclosed
US-20040097590-A1 Oxazolyl-arylpropionic acid derivatives and their use as ppar agonists BROOKS DAWN ALISA (US) 2004-05-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040097590-A1 Oxazolyl-arylpropionic acid derivatives and their use as ppar agonists PPARA, PPARG, PPARD PPARG 2/4885PPARA 1/4885PPARD 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.